BIOMAT Database Logo BIOMAT Database Logo

Comparison of GC-NCI MS, GC-ICP-MS, and GC-EI MS-MS for the determination of PBDEs in water samples according to the Water Framework Directive. 2015

Adriana Gonzalez-Gago, and Daniel Pröfrock, and Andreas Prange
Department Marine Bioanalytical Chemistry, Helmholtz Zentrum Geesthacht - Zentrum für Material und Küstenforschung, Institute of Coastal Research, Max-Planck Str. 1, 21502, Geesthacht, Germany.

The Water Framework Directive (WFD) includes some polybrominated diphenyl ethers (PBDEs) in the list of priority substances that must be measured in surface waters at very low concentrations. The typical approaches applied to the determination of PBDEs in environmental samples might not meet the demanding requirements of the WFD. In this work, the instrumental capabilities of the mass-spectrometry (MS) techniques most frequently used in the determination of PBDEs, namely gas chromatography-negative-chemical-ionisation MS (GC-NCI MS) and GC-electrospray-ionisation tandem MS (EI MS-MS), are evaluated in comparison with highly sensitive GC-inductively-coupled-plasma MS (ICP-MS) for the reliable determination of PBDEs according to the WFD. Three analytical methods based on the liquid-liquid extraction of water samples and measurement of the extracts by GC-NCI MS, GC-EI MS-MS, or GC-ICP-MS are described. The priority PBDEs were quantified in different types of water sample by means of isotope-dilution mass spectrometry (IDMS) using (81)Br-labelled or (13)C-labelled PBDEs spikes, depending on the selected ionisation source. The three proposed methods met the requirements of the European legislation in terms of LOQs and expanded uncertainties. The determination method using (81)Br-labelled PBDEs and GC-ICP-MS had the highest sensitivity and the lowest instrumental limits of detection and expanded uncertainties.

UI MeSH Term Description Entries
D008401 Gas Chromatography-Mass Spectrometry A microanalytical technique combining mass spectrometry and gas chromatography for the qualitative as well as quantitative determinations of compounds. Chromatography, Gas-Liquid-Mass Spectrometry,Chromatography, Gas-Mass Spectrometry,GCMS,Spectrometry, Mass-Gas Chromatography,Spectrum Analysis, Mass-Gas Chromatography,Gas-Liquid Chromatography-Mass Spectrometry,Mass Spectrometry-Gas Chromatography,Chromatography, Gas Liquid Mass Spectrometry,Chromatography, Gas Mass Spectrometry,Chromatography, Mass Spectrometry-Gas,Chromatography-Mass Spectrometry, Gas,Chromatography-Mass Spectrometry, Gas-Liquid,Gas Chromatography Mass Spectrometry,Gas Liquid Chromatography Mass Spectrometry,Mass Spectrometry Gas Chromatography,Spectrometries, Mass-Gas Chromatography,Spectrometry, Gas Chromatography-Mass,Spectrometry, Gas-Liquid Chromatography-Mass,Spectrometry, Mass Gas Chromatography,Spectrometry-Gas Chromatography, Mass,Spectrum Analysis, Mass Gas Chromatography
D005411 Flame Retardants Materials applied to fabrics, bedding, furniture, plastics, etc. to retard their burning; many may leach out and cause allergies or other harm. Fire Retardant,Fire Retardants,Fireproofing Agent,Fireproofing Agents,Flame Retardant,Agent, Fireproofing,Agents, Fireproofing,Retardant, Fire,Retardant, Flame,Retardants, Fire,Retardants, Flame
D014867 Water A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) Hydrogen Oxide
D014874 Water Pollutants, Chemical Chemical compounds which pollute the water of rivers, streams, lakes, the sea, reservoirs, or other bodies of water. Chemical Water Pollutants,Landfill Leachate,Leachate, Landfill,Pollutants, Chemical Water
D053719 Tandem Mass Spectrometry A mass spectrometry technique using two (MS/MS) or more mass analyzers. With two in tandem, the precursor ions are mass-selected by a first mass analyzer, and focused into a collision region where they are then fragmented into product ions which are then characterized by a second mass analyzer. A variety of techniques are used to separate the compounds, ionize them, and introduce them to the first mass analyzer. For example, for in GC-MS/MS, GAS CHROMATOGRAPHY-MASS SPECTROMETRY is involved in separating relatively small compounds by GAS CHROMATOGRAPHY prior to injecting them into an ionization chamber for the mass selection. Mass Spectrometry-Mass Spectrometry,Mass Spectrometry Mass Spectrometry,Mass Spectrometry, Tandem
D055768 Halogenated Diphenyl Ethers Compounds that contain two halogenated benzene rings linked via an OXYGEN atom. Many polybrominated diphenyl ethers are used as FLAME RETARDANTS. Brominated Diphenyl Ethers,Chlorinated Diphenyl Ethers,Fluorinated Diphenyl Ethers,Iodinated Diphenyl Ethers,PBDE Compounds,PBDEs,PCDE Compounds,PCDEs,Polybrominated Diphenyl Ethers,Diphenyl Ethers, Brominated,Diphenyl Ethers, Chlorinated,Diphenyl Ethers, Fluorinated,Diphenyl Ethers, Halogenated,Diphenyl Ethers, Iodinated,Diphenyl Ethers, Polybrominated,Ethers, Brominated Diphenyl,Ethers, Chlorinated Diphenyl,Ethers, Fluorinated Diphenyl,Ethers, Halogenated Diphenyl,Ethers, Iodinated Diphenyl,Ethers, Polybrominated Diphenyl
D059625 Liquid-Liquid Extraction The removal of a soluble component from a liquid mixture by contact with a second liquid, immiscible with the carrier liquid, in which the component is preferentially soluble. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed) Liquid Phase Extraction,Extraction, Liquid Phase,Extraction, Liquid-Liquid,Extractions, Liquid Phase,Extractions, Liquid-Liquid,Liquid Liquid Extraction,Liquid Phase Extractions,Liquid-Liquid Extractions,Phase Extraction, Liquid,Phase Extractions, Liquid
D021241 Spectrometry, Mass, Electrospray Ionization A mass spectrometry technique used for analysis of nonvolatile compounds such as proteins and macromolecules. The technique involves preparing electrically charged droplets from analyte molecules dissolved in solvent. The electrically charged droplets enter a vacuum chamber where the solvent is evaporated. Evaporation of solvent reduces the droplet size, thereby increasing the coulombic repulsion within the droplet. As the charged droplets get smaller, the excess charge within them causes them to disintegrate and release analyte molecules. The volatilized analyte molecules are then analyzed by mass spectrometry. ESI Mass Spectrometry,Electrospray Ionization Mass Spectrometry,Mass Spectrometry, ESI,Spectrometry, ESI Mass

Related Publications

Adriana Gonzalez-Gago, and Daniel Pröfrock, and Andreas Prange
Methods for the analysis of organophosphorus flame retardants-Comparison of GC-EI-MS, GC-NCI-MS, LC-ESI-MS/MS, and LC-APCI-MS/MS.
April 2018, Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering,
Adriana Gonzalez-Gago, and Daniel Pröfrock, and Andreas Prange
Experimental design for TBT quantification by isotope dilution SPE-GC-ICP-MS under the European water framework directive.
March 2015, Talanta,
Adriana Gonzalez-Gago, and Daniel Pröfrock, and Andreas Prange
Integration of GC/EI-MS and GC/NCI-MS for simultaneous quantitative determination of opiates, amphetamines, MDMA, ketamine, and metabolites in human hair.
July 2008, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences,
Adriana Gonzalez-Gago, and Daniel Pröfrock, and Andreas Prange
Determination of 117 endocrine disruptors (EDCs) in water using SBSE TD-GC-MS/MS under the European Water Framework Directive.
August 2020, Analytical and bioanalytical chemistry,
Adriana Gonzalez-Gago, and Daniel Pröfrock, and Andreas Prange
Comparative determination of methyl mercury in whole blood samples using GC-ICP-MS and GC-MS techniques.
August 2009, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences,
Adriana Gonzalez-Gago, and Daniel Pröfrock, and Andreas Prange
Synthesis of 81Br-labeled polybrominated diphenyl ethers and their characterization using GC(EI)MS and GC(ICP)MS.
April 2010, Analytical chemistry,
Adriana Gonzalez-Gago, and Daniel Pröfrock, and Andreas Prange
GC/EI-MS method for the determination of phytosterols in vegetable oils.
January 2022, Analytical and bioanalytical chemistry,
Adriana Gonzalez-Gago, and Daniel Pröfrock, and Andreas Prange
Development of an analytical procedure for the determination of polybrominated diphenyl ethers in environmental water samples by GC-ICP-MS.
May 2014, Analytica chimica acta,
Adriana Gonzalez-Gago, and Daniel Pröfrock, and Andreas Prange
Determination of butyltin compounds in environmental samples by isotope-dilution GC-ICP-MS.
July 2002, Analytical and bioanalytical chemistry,
Adriana Gonzalez-Gago, and Daniel Pröfrock, and Andreas Prange
Fragmentation of Dicarboxylic and Tricarboxylic Acids in the Krebs Cycle Using GC-EI-MS and GC-EI-MS/MS.
January 2019, Mass spectrometry (Tokyo, Japan),
Copied contents to your clipboard!