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Enhancing the efficacy of cation-independent mannose 6-phosphate receptor inhibitors by intracellular delivery. 2016
Vipul Agarwal, and
Priyanka Toshniwal, and
Natalie E Smith, and
Nicole M Smith, and
Binbin Li, and
Tristan D Clemons, and
Lindsay T Byrne, and
Foteini Kakulas, and
Fiona M Wood, and
Mark Fear, and
Ben Corry, and
K Swaminathan Iyer
School of Chemistry and Biochemistry, The University of Western Australia, Crawley, Western Australia, Australia. swaminatha.iyer@uwa.edu.au.
Intracellular delivery of M6P/IGFII receptor inhibitors exhibits better efficacy than extracellular inhibitors to regulate TGFβ1 mediated upregulation of profibrotic marker, collagen I.
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