Ruptured intracranial aneurysms: a 12-month prospective study. 1989

E A Popovic, and K Siu
Neurosurgery Unit, Monash Medical Centre, Prince Henry's Hospital Campus, Melbourne, VIC.

A prospective study was undertaken of all cases of ruptured intracranial aneurysms that presented to Monash Medical Centre's neurosurgical service over a 12-month period. Forty-seven patients had proved aneurysmal subarachnoid haemorrhages. The management mortality rate over all was 23.4%. Forty patients underwent definitive treatment by craniotomy and clipping of the aneurysm; the operative mortality rate was 12.5%. Excellent results were obtained in all 22 patients whose clinical grade was good on the day of surgery; half these patients underwent operation within 72 hours of the episode. Sixty per cent of all patients were discharged from hospital without any neurological deficit; virtually all the remaining patients' morbidity and mortality were attributable to aneurysmal rebleeding and cerebral vasospasm. Early surgery for aneurysms has been the trend in North America, Europe and Japan and the results that were obtained in this study support early surgery in patients with a good clinical grade; further experience is needed to establish the optimal timing of surgery in patients with a worse clinical grade.

UI MeSH Term Description Entries
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D011183 Postoperative Complications Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery. Complication, Postoperative,Complications, Postoperative,Postoperative Complication
D011379 Prognosis A prediction of the probable outcome of a disease based on a individual's condition and the usual course of the disease as seen in similar situations. Prognostic Factor,Prognostic Factors,Factor, Prognostic,Factors, Prognostic,Prognoses
D011446 Prospective Studies Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group. Prospective Study,Studies, Prospective,Study, Prospective
D002532 Intracranial Aneurysm Abnormal outpouching in the wall of intracranial blood vessels. Most common are the saccular (berry) aneurysms located at branch points in CIRCLE OF WILLIS at the base of the brain. Vessel rupture results in SUBARACHNOID HEMORRHAGE or INTRACRANIAL HEMORRHAGES. Giant aneurysms (>2.5 cm in diameter) may compress adjacent structures, including the OCULOMOTOR NERVE. (From Adams et al., Principles of Neurology, 6th ed, p841) Aneurysm, Cerebral,Aneurysm, Intracranial,Basilar Artery Aneurysm,Berry Aneurysm,Brain Aneurysm,Cerebral Aneurysm,Giant Intracranial Aneurysm,Mycotic Aneurysm, Intracranial,Aneurysm, Anterior Cerebral Artery,Aneurysm, Anterior Communicating Artery,Aneurysm, Basilar Artery,Aneurysm, Middle Cerebral Artery,Aneurysm, Posterior Cerebral Artery,Aneurysm, Posterior Communicating Artery,Anterior Cerebral Artery Aneurysm,Anterior Communicating Artery Aneurysm,Middle Cerebral Artery Aneurysm,Posterior Cerebral Artery Aneurysm,Posterior Communicating Artery Aneurysm,Aneurysm, Berry,Aneurysm, Brain,Aneurysm, Giant Intracranial,Aneurysm, Intracranial Mycotic,Aneurysms, Basilar Artery,Aneurysms, Berry,Aneurysms, Brain,Aneurysms, Cerebral,Aneurysms, Giant Intracranial,Aneurysms, Intracranial,Aneurysms, Intracranial Mycotic,Artery Aneurysm, Basilar,Artery Aneurysms, Basilar,Basilar Artery Aneurysms,Berry Aneurysms,Brain Aneurysms,Cerebral Aneurysms,Giant Intracranial Aneurysms,Intracranial Aneurysm, Giant,Intracranial Aneurysms,Intracranial Aneurysms, Giant,Intracranial Mycotic Aneurysm,Intracranial Mycotic Aneurysms,Mycotic Aneurysms, Intracranial
D002536 Cerebral Arteries The arterial blood vessels supplying the CEREBRUM. Arteries, Cerebral,Artery, Cerebral,Cerebral Artery
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000293 Adolescent A person 13 to 18 years of age. Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D000368 Aged A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available. Elderly

Related Publications

E A Popovic, and K Siu
January 1995, British journal of neurosurgery,
E A Popovic, and K Siu
December 1968, Applied therapeutics,
E A Popovic, and K Siu
November 1956, The Ulster medical journal,
E A Popovic, and K Siu
November 1985, Journal of the Medical Association of Georgia,
E A Popovic, and K Siu
May 1971, Proceedings of the Royal Society of Medicine,
E A Popovic, and K Siu
April 1983, Journal of neurology, neurosurgery, and psychiatry,
E A Popovic, and K Siu
September 1983, Journal of neurology, neurosurgery, and psychiatry,
E A Popovic, and K Siu
April 1983, Surgical neurology,
E A Popovic, and K Siu
August 1946, Journal. Iowa State Medical Society,
E A Popovic, and K Siu
September 1989, European heart journal,
Copied contents to your clipboard!