-transparent.png){kind=logo}
Synthesis of constrained analogues of tryptophan. 2015
Elisabetta Rossi, and
Valentina Pirovano, and
Marco Negrato, and
Giorgio Abbiati, and
Monica Dell'Acqua
Dipartimento di Scienze Farmaceutiche, Sezione di Chimica Generale e Organica "A. Marchesini", Università degli Studi di Milano, Via Venezian, 21, 20133 Milano, Italy.
A Lewis acid-catalysed diastereoselective [4 + 2] cycloaddition of vinylindoles and methyl 2-acetamidoacrylate, leading to methyl 3-acetamido-1,2,3,4-tetrahydrocarbazole-3-carboxylate derivatives, is described. Treatment of the obtained cycloadducts under hydrolytic conditions results in the preparation of a small library of compounds bearing the free amino acid function at C-3 and pertaining to the class of constrained tryptophan analogues.
| UI | MeSH Term | Description | Entries |
|---|
Related Publications
Elisabetta Rossi, and
Valentina Pirovano, and
Marco Negrato, and
Giorgio Abbiati, and
Monica Dell'Acqua
June 2006,
The Journal of organic chemistry,
Elisabetta Rossi, and
Valentina Pirovano, and
Marco Negrato, and
Giorgio Abbiati, and
Monica Dell'Acqua
June 2000,
Journal of medicinal chemistry,
Elisabetta Rossi, and
Valentina Pirovano, and
Marco Negrato, and
Giorgio Abbiati, and
Monica Dell'Acqua
May 2000,
Journal of medicinal chemistry,
Elisabetta Rossi, and
Valentina Pirovano, and
Marco Negrato, and
Giorgio Abbiati, and
Monica Dell'Acqua
June 1974,
Analytical biochemistry,
Elisabetta Rossi, and
Valentina Pirovano, and
Marco Negrato, and
Giorgio Abbiati, and
Monica Dell'Acqua
August 2010,
Organic & biomolecular chemistry,
Elisabetta Rossi, and
Valentina Pirovano, and
Marco Negrato, and
Giorgio Abbiati, and
Monica Dell'Acqua
August 2007,
Organic & biomolecular chemistry,
Elisabetta Rossi, and
Valentina Pirovano, and
Marco Negrato, and
Giorgio Abbiati, and
Monica Dell'Acqua
March 2006,
Tetrahedron letters,
Elisabetta Rossi, and
Valentina Pirovano, and
Marco Negrato, and
Giorgio Abbiati, and
Monica Dell'Acqua
September 2009,
Magnetic resonance in chemistry : MRC,
Elisabetta Rossi, and
Valentina Pirovano, and
Marco Negrato, and
Giorgio Abbiati, and
Monica Dell'Acqua
July 2016,
Journal of the American Chemical Society,
Elisabetta Rossi, and
Valentina Pirovano, and
Marco Negrato, and
Giorgio Abbiati, and
Monica Dell'Acqua
May 2003,
Organic letters,
