BIOMAT Database Logo BIOMAT Database Logo

MDV3100: Tritium labeling at high specific activity. 2016

Chang Byon, and Sarvajit Chakravarty, and Crist N Filer, and Rajendra Jain, and Mario P Maniscalco
PerkinElmer Health Sciences Inc., 940 Winter Street, Waltham, MA 02451, USA.

An efficient method is described to tritiate MDV3100 at high specific activity.

UI MeSH Term Description Entries
D007553 Isotope Labeling Techniques for labeling a substance with a stable or radioactive isotope. It is not used for articles involving labeled substances unless the methods of labeling are substantively discussed. Tracers that may be labeled include chemical substances, cells, or microorganisms. Isotope Labeling, Stable,Isotope-Coded Affinity Tagging,Isotopically-Coded Affinity Tagging,Affinity Tagging, Isotope-Coded,Affinity Tagging, Isotopically-Coded,Isotope Coded Affinity Tagging,Labeling, Isotope,Labeling, Stable Isotope,Stable Isotope Labeling,Tagging, Isotope-Coded Affinity,Tagging, Isotopically-Coded Affinity
D008422 Materials Testing The testing of materials and devices, especially those used for PROSTHESES AND IMPLANTS; SUTURES; TISSUE ADHESIVES; etc., for hardness, strength, durability, safety, efficacy, and biocompatibility. Biocompatibility Testing,Biocompatible Materials Testing,Hemocompatibility Testing,Testing, Biocompatible Materials,Testing, Hemocompatible Materials,Hemocompatibility Testings,Hemocompatible Materials Testing,Materials Testing, Biocompatible,Materials Testing, Hemocompatible,Testing, Biocompatibility,Testing, Hemocompatibility,Testing, Materials,Testings, Biocompatibility
D009570 Nitriles Organic compounds containing the -CN radical. The concept is distinguished from CYANIDES, which denotes inorganic salts of HYDROGEN CYANIDE. Nitrile
D010669 Phenylthiohydantoin Thiohydantoin benzene derivative.
D011829 Radiation Dosage The amount of radiation energy that is deposited in a unit mass of material, such as tissues of plants or animal. In RADIOTHERAPY, radiation dosage is expressed in gray units (Gy). In RADIOLOGIC HEALTH, the dosage is expressed by the product of absorbed dose (Gy) and quality factor (a function of linear energy transfer), and is called radiation dose equivalent in sievert units (Sv). Sievert Units,Dosage, Radiation,Gray Units,Gy Radiation,Sv Radiation Dose Equivalent,Dosages, Radiation,Radiation Dosages,Units, Gray,Units, Sievert
D001549 Benzamides BENZOIC ACID amides.
D014316 Tritium The radioactive isotope of hydrogen also known as hydrogen-3. It contains two NEUTRONS and one PROTON in its nucleus and decays to produce low energy BETA PARTICLES. Hydrogen-3,Hydrogen 3
D019275 Radiopharmaceuticals Compounds that are used in medicine as sources of radiation for radiotherapy and for diagnostic purposes. They have numerous uses in research and industry. (Martindale, The Extra Pharmacopoeia, 30th ed, p1161) Radiopharmaceutical
D066244 Proton Magnetic Resonance Spectroscopy Spectroscopy technique which measures changes in organic compounds by tracking the spectral energy of absorption of HYDROGEN atoms. 1H NMR,1H-MRS,1H-NMR

Related Publications

Chang Byon, and Sarvajit Chakravarty, and Crist N Filer, and Rajendra Jain, and Mario P Maniscalco
Spiperone: Tritium labelling at high specific activity.
May 2019, Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine,
Chang Byon, and Sarvajit Chakravarty, and Crist N Filer, and Rajendra Jain, and Mario P Maniscalco
S-(4-nitrobenzyl)-6-thioinosine: Tritium labelling at high specific activity.
July 2020, Journal of labelled compounds & radiopharmaceuticals,
Chang Byon, and Sarvajit Chakravarty, and Crist N Filer, and Rajendra Jain, and Mario P Maniscalco
[Tritium-labeled dithranol with high specific activity].
January 1987, Dermatologische Monatschrift,
Chang Byon, and Sarvajit Chakravarty, and Crist N Filer, and Rajendra Jain, and Mario P Maniscalco
Tritium labeling of proteins to high specific radioactivity by reduction methylation.
September 1980, The Journal of biological chemistry,
Chang Byon, and Sarvajit Chakravarty, and Crist N Filer, and Rajendra Jain, and Mario P Maniscalco
Specific tritium labeling of gangliosides at the 3-position of sphingosines.
November 1981, Journal of lipid research,
Chang Byon, and Sarvajit Chakravarty, and Crist N Filer, and Rajendra Jain, and Mario P Maniscalco
Tritium labelling of several potent fluorinated antipsychotic drugs at high specific activity.
July 2007, Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine,
Chang Byon, and Sarvajit Chakravarty, and Crist N Filer, and Rajendra Jain, and Mario P Maniscalco
Tritium labelling of two potent dopamine D2 receptor agonists at high specific activity.
June 2021, Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine,
Chang Byon, and Sarvajit Chakravarty, and Crist N Filer, and Rajendra Jain, and Mario P Maniscalco
Control of self-irradiation decomposition of tritium-labelled compounds at high specific activity.
January 1966, Nature,
Chang Byon, and Sarvajit Chakravarty, and Crist N Filer, and Rajendra Jain, and Mario P Maniscalco
Biologically active equine estrogens and sulfate conjugates labelled with tritium at high specific activity.
January 2013, Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine,
Chang Byon, and Sarvajit Chakravarty, and Crist N Filer, and Rajendra Jain, and Mario P Maniscalco
Site-Specific Tritium Labeling at the Predefined Internal Position of the Chemically-Modified RNA.
January 2023, Chemical & pharmaceutical bulletin,
Copied contents to your clipboard!