Biomaterial Database

Clinical Reasoning: A 64-year-old man with progressive paraspinal muscle weakness. 2016

Raphael Schneider, and Claude Steriade, and Peter Ashby, and Tim-Rasmus Kiehl

From the Department of Postgraduate Medical Education (R.S., C.S.), Department of Medicine, Division of Neurology, University Health Network (P.A.), and Department of Laboratory Medicine and Pathobiology (T.-R.K.), University of Toronto; and Department of Pathology (T.-R.K.), University Health Network, Toronto, ON, Canada. raphael.schneider@utoronto.ca.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D004576	Electromyography	Recording of the changes in electric potential of muscle by means of surface or needle electrodes.	Electromyogram,Surface Electromyography,Electromyograms,Electromyographies,Electromyographies, Surface,Electromyography, Surface,Surface Electromyographies
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D017696	Myopathies, Nemaline	A group of inherited congenital myopathic conditions characterized clinically by weakness, hypotonia, and prominent hypoplasia of proximal muscles including the face. Muscle biopsy reveals large numbers of rod-shaped structures beneath the muscle fiber plasma membrane. This disorder is genetically heterogeneous and may occasionally present in adults. (Adams et al., Principles of Neurology, 6th ed, p1453)	Myopathy, Nemaline,Myopathy, Rod,Myopathy, Rod-Body,Nemaline Myopathies,Adult Onset Nemaline Myopathy,Autosomal Dominant Nemaline Myopathy,Autosomal Recessive Nemaline Myopathy,Childhood Onset Nemaline Myopathy,Late Onset Nemaline Myopathy,Nemaline Body Disease,Nemaline Myopathy,Nemaline Myopathy, Adult Onset,Nemaline Myopathy, Autosomal Dominant,Nemaline Myopathy, Autosomal Recessive,Nemaline Myopathy, Childhood Onset,Nemaline Myopathy, Late Onset,Nemaline Rod Disease,Rod Body Disease,Rod Myopathy,Rod-Body Myopathy,Myopathies, Rod,Myopathies, Rod-Body,Myopathy, Rod Body,Rod Body Myopathy,Rod Myopathies,Rod-Body Myopathies
D018908	Muscle Weakness	A vague complaint of debility, fatigue, or exhaustion attributable to weakness of various muscles. The weakness can be characterized as subacute or chronic, often progressive, and is a manifestation of many muscle and neuromuscular diseases. (From Wyngaarden et al., Cecil Textbook of Medicine, 19th ed, p2251)	Muscular Weakness,Muscle Weaknesses,Muscular Weaknesses,Weakness, Muscle,Weakness, Muscular,Weaknesses, Muscle,Weaknesses, Muscular
D064170	Paraspinal Muscles	Deep muscles in the BACK whose function is to extend and rotate the SPINE and maintain POSTURE. It consists splenius, semispinalis, multifidus, rotatores, interspinales, intertransversarii and sacrospinalis.	Deep Muscles of the Back,Interspinales,Intertransversales,Intertransversarii,Intrinsic Muscles of the Back,Multifidus,Rotatores,Sacrospinalis Iliocostalis,Sacrospinalis Longissimus,Sacrospinalis Spinalis,Semispinalis,Splenius,Iliocostali, Sacrospinalis,Iliocostalis, Sacrospinalis,Interspinale,Intertransversale,Intertransversarius,Longissimus, Sacrospinalis,Muscle, Paraspinal,Muscles, Paraspinal,Paraspinal Muscle,Rotatore,Sacrospinalis Iliocostali,Sacrospinalis Spinali,Semispinali,Spinali, Sacrospinalis,Spinalis, Sacrospinalis