-transparent.png){kind=logo}
The field of neural transplantation has moved rapidly forward in the last decade. Initially, fetal cells were used as implants to investigate their potential to ameliorate deficits in animal models of Parkinson's disease. However, because of the moral and legal problems associated with the use of fetal tissues in humans, alternative sources of donor tissue were sought which possessed the structural and functional characteristics needed to improve motor function in Parkinsonian patients. To date, one of the most promising tissues being investigated is the adrenal medulla, whose chromaffin cells possess an inherent plasticity of form and function. Transplanted chromaffin cells currently are being studied by a variety of approaches, including electron microscopy, in mouse, rat, and primate models of Parkinson's disease. An overview of the role of the chromaffin cell in this exciting and clinically important arena is briefly reviewed, with an emphasis on the fine structure of implanted chromaffin cells.
J T Hansen, and
G Y Bing, and
M F Notter, and
J H Kordower, and
M S Fiandaca, and
D M Gash
January 1990,
Advances in neurology,
J T Hansen, and
G Y Bing, and
M F Notter, and
J H Kordower, and
M S Fiandaca, and
D M Gash
January 1990,
Advances in neurology,
J T Hansen, and
G Y Bing, and
M F Notter, and
J H Kordower, and
M S Fiandaca, and
D M Gash
June 2012,
Movement disorders : official journal of the Movement Disorder Society,
J T Hansen, and
G Y Bing, and
M F Notter, and
J H Kordower, and
M S Fiandaca, and
D M Gash
January 1990,
Advances and technical standards in neurosurgery,
J T Hansen, and
G Y Bing, and
M F Notter, and
J H Kordower, and
M S Fiandaca, and
D M Gash
January 1989,
Acta neurologica Scandinavica. Supplementum,
J T Hansen, and
G Y Bing, and
M F Notter, and
J H Kordower, and
M S Fiandaca, and
D M Gash
January 1990,
Progress in brain research,
J T Hansen, and
G Y Bing, and
M F Notter, and
J H Kordower, and
M S Fiandaca, and
D M Gash
October 1987,
JAMA,
J T Hansen, and
G Y Bing, and
M F Notter, and
J H Kordower, and
M S Fiandaca, and
D M Gash
April 1988,
British medical journal (Clinical research ed.),
J T Hansen, and
G Y Bing, and
M F Notter, and
J H Kordower, and
M S Fiandaca, and
D M Gash
January 2007,
Handbook of clinical neurology,
J T Hansen, and
G Y Bing, and
M F Notter, and
J H Kordower, and
M S Fiandaca, and
D M Gash
January 2011,
Parkinson's disease,
