Biomaterial Database

[Study on the relationships between dietary cholesterol and serum cholesterol among Chinese adults]. 2015

Chang Su, and Xiaofang Jia, and Zhihong Wang, and Huijun Wang, and Bing Zhang

National Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Beijing 100050, China.

OBJECTIVE To describe the relationships between dietary cholesterol and serum cholesterol among Chinese adults. METHODS Data used in the present study was from the China Health and Nutrition Study (CHNS). Chinese adults, 18 to 65 year olds who participated in the 2009 CHNS with complete individual information were included in the study. Correlation of dietary cholesterol and serum cholesterol among different sex groups was described to explore the effect of dietary cholesterol intake on the level of serum cholesterol as well as to examine the effect of higher intake of dietary cholesterol related to hypercholesterolemia. RESULTS Results from the correlation analysis indicated that dietary cholesterol appeared a highly positive correlation (P < 0.05) with serum total cholesterol (TC) and low density lipoprotein cholesterol (LDL-C). Data from the multiple regression analysis showed that dietary cholesterol intake was an important factor that affecting the serum TC (P < 0.05) in both males and females but LDL-C was only in females (P = 0.01). After adjusting for potential confounders, the high intake of dietary cholesterol (≥ 300 mg/d) had higher risks for developing hypercholesterolemia in both males and females (OR = 1.21, 95% CI: 1.03-1.42, P = 0.019; OR = 1.18, 95% CI: 1.00-1.40, P = 0.044), respectively. CONCLUSIONS Dietary cholesterol intake seemed to correlate with the serum cholesterol level, and hypercholesterolemia should be prevented through reducing the dietary cholesterol among Chinese adults.

UI	MeSH Term	Description	Entries
D008078	Cholesterol, LDL	Cholesterol which is contained in or bound to low density lipoproteins (LDL), including CHOLESTEROL ESTERS and free cholesterol.	LDL Cholesterol,Cholesteryl Linoleate, LDL,LDL Cholesteryl Linoleate,Low Density Lipoprotein Cholesterol,beta-Lipoprotein Cholesterol,Cholesterol, beta-Lipoprotein,beta Lipoprotein Cholesterol
D008297	Male		Males
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D012044	Regression Analysis	Procedures for finding the mathematical function which best describes the relationship between a dependent variable and one or more independent variables. In linear regression (see LINEAR MODELS) the relationship is constrained to be a straight line and LEAST-SQUARES ANALYSIS is used to determine the best fit. In logistic regression (see LOGISTIC MODELS) the dependent variable is qualitative rather than continuously variable and LIKELIHOOD FUNCTIONS are used to find the best relationship. In multiple regression, the dependent variable is considered to depend on more than a single independent variable.	Regression Diagnostics,Statistical Regression,Analysis, Regression,Analyses, Regression,Diagnostics, Regression,Regression Analyses,Regression, Statistical,Regressions, Statistical,Statistical Regressions
D002681	China	A country spanning from central Asia to the Pacific Ocean.	Inner Mongolia,Manchuria,People's Republic of China,Sinkiang,Mainland China
D002791	Cholesterol, Dietary	Cholesterol present in food, especially in animal products.	Dietary Cholesterol
D005260	Female		Females
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D006937	Hypercholesterolemia	A condition with abnormally high levels of CHOLESTEROL in the blood. It is defined as a cholesterol value exceeding the 95th percentile for the population.	Hypercholesteremia,Elevated Cholesterol,High Cholesterol Levels,Cholesterol Level, High,Cholesterol Levels, High,Cholesterol, Elevated,Cholesterols, Elevated,Elevated Cholesterols,High Cholesterol Level,Hypercholesteremias,Hypercholesterolemias,Level, High Cholesterol,Levels, High Cholesterol
D000293	Adolescent	A person 13 to 18 years of age.	Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths