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To test the hypothesis that an increase in fetal blood viscosity is associated with an increase in resistance to flow, the effect on Doppler flow velocity waveforms of percutaneous umbilical blood sampling and intravascular transfusion was studied in 20 patients undergoing a total of 35 procedures. All but four of the 22 transfusions were associated with a decrease in resistance to flow, as shown by a reduction in the umbilical artery systolic/diastolic ratio, and this also occurred on 10 of the 13 occasions when blood sampling only was performed. These findings suggest that acute changes in blood viscosity following intravascular transfusion are not associated with an increase in resistance to flow as assessed by Doppler velocimetry. Umbilical blood sampling per se may be associated with a humorally mediated reduction in placental vascular resistance to flow.
K P Hanretty, and
M J Whittle, and
D H Gilmore, and
M B McNay, and
C A Howie, and
P C Rubin
September 1990,
British journal of obstetrics and gynaecology,
K P Hanretty, and
M J Whittle, and
D H Gilmore, and
M B McNay, and
C A Howie, and
P C Rubin
September 1996,
Acta obstetricia et gynecologica Scandinavica,
K P Hanretty, and
M J Whittle, and
D H Gilmore, and
M B McNay, and
C A Howie, and
P C Rubin
May 1994,
American journal of obstetrics and gynecology,
K P Hanretty, and
M J Whittle, and
D H Gilmore, and
M B McNay, and
C A Howie, and
P C Rubin
January 1994,
Journal of clinical ultrasound : JCU,
K P Hanretty, and
M J Whittle, and
D H Gilmore, and
M B McNay, and
C A Howie, and
P C Rubin
February 1992,
British journal of obstetrics and gynaecology,
K P Hanretty, and
M J Whittle, and
D H Gilmore, and
M B McNay, and
C A Howie, and
P C Rubin
April 2003,
Obstetrics and gynecology,
K P Hanretty, and
M J Whittle, and
D H Gilmore, and
M B McNay, and
C A Howie, and
P C Rubin
January 1994,
Journal of clinical ultrasound : JCU,
K P Hanretty, and
M J Whittle, and
D H Gilmore, and
M B McNay, and
C A Howie, and
P C Rubin
December 1987,
Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke,
K P Hanretty, and
M J Whittle, and
D H Gilmore, and
M B McNay, and
C A Howie, and
P C Rubin
April 1989,
Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine,
K P Hanretty, and
M J Whittle, and
D H Gilmore, and
M B McNay, and
C A Howie, and
P C Rubin
April 1990,
Obstetrics and gynecology,
