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Feature selection and oversampling in analysis of clinical data for extubation readiness in extreme preterm infants. 2015

Pascale Gourdeau, and Lara Kanbar, and Wissam Shalish, and Guilherme Sant'Anna, and Robert Kearney, and Doina Precup

We present an approach for the analysis of clinical data from extremely preterm infants, in order to determine if they are ready to be removed from invasive endotracheal mechanical ventilation. The data includes over 100 clinical features, and the subject population is naturally quite small. To address this problem, we use feature selection, specifically mutual information, in order to choose a small subset of informative features. The other challenge we address is class imbalance, as there are many more babies that succeed extubation than those who fail. To handle this problem, we use SMOTE, an algorithm which creates synthetic examples of the minority class.

UI MeSH Term Description Entries
D007231 Infant, Newborn An infant during the first 28 days after birth. Neonate,Newborns,Infants, Newborn,Neonates,Newborn,Newborn Infant,Newborn Infants
D007234 Infant, Premature A human infant born before 37 weeks of GESTATION. Neonatal Prematurity,Premature Infants,Preterm Infants,Infant, Preterm,Infants, Premature,Infants, Preterm,Premature Infant,Prematurity, Neonatal,Preterm Infant
D007235 Infant, Premature, Diseases Diseases that occur in PREMATURE INFANTS.
D007442 Intubation, Intratracheal A procedure involving placement of a tube into the trachea through the mouth or nose in order to provide a patient with oxygen and anesthesia. Intubation, Endotracheal,Endotracheal Intubation,Endotracheal Intubations,Intratracheal Intubation,Intratracheal Intubations,Intubations, Endotracheal,Intubations, Intratracheal
D012121 Respiration, Artificial Any method of artificial breathing that employs mechanical or non-mechanical means to force the air into and out of the lungs. Artificial respiration or ventilation is used in individuals who have stopped breathing or have RESPIRATORY INSUFFICIENCY to increase their intake of oxygen (O2) and excretion of carbon dioxide (CO2). Ventilation, Mechanical,Mechanical Ventilation,Artificial Respiration,Artificial Respirations,Mechanical Ventilations,Respirations, Artificial,Ventilations, Mechanical
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D060666 Airway Extubation Removal of an endotracheal tube from the patient. Endotracheal Extubation,Extubation, Intratracheal,Tracheal Extubation,Airway Extubations,Endotracheal Extubations,Extubation, Airway,Extubation, Endotracheal,Extubation, Tracheal,Extubations, Airway,Extubations, Endotracheal,Extubations, Intratracheal,Extubations, Tracheal,Intratracheal Extubation,Intratracheal Extubations,Tracheal Extubations

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