Biomaterial Database

Necrotizing fasciitis. 1977

S M Roser, and A W Chow, and F A Brady

Necrotizing fasciitis is a relatively uncommon severe soft tissue infection that is characterized by rapid widespread superficial fascial necrosis with undermining of surrounding soft tissue. Recent advances in anaerobic culture techniques have allowed identification of anaerobic organisms, which are now considered to have a vital role in the pathogenesis of this soft tissue infection. Therapy requires both rapid institution of a high level of antibiotics and a radical surgical incision and drainage procedure. All of the aerobic and anaerobic organisms isolated in the reported case of necrotizing fasciitis arising from a periapically infected mandibular third molar demonstrated in vitro sensitivity to penicillin.

UI	MeSH Term	Description	Entries
D007249	Inflammation	A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.	Innate Inflammatory Response,Inflammations,Inflammatory Response, Innate,Innate Inflammatory Responses
D008297	Male		Males
D009333	Neck	The part of a human or animal body connecting the HEAD to the rest of the body.	Necks
D009336	Necrosis	The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
D010482	Periapical Abscess	Acute or chronic inflammation of tissues surrounding the apical portion of a tooth, associated with the collection of pus, resulting from infection following pulp infection through a carious lesion or as a result of an injury causing pulp necrosis. (Dorland, 27th ed)	Abscess, Periapical,Alveolar Abscess, Apical,Dentoalveolar Abscess, Apical,Periapical Periodontitis, Suppurative,Periodontitis, Apical, Suppurative,Abscess, Apical Alveolar,Abscess, Apical Dentoalveolar,Abscesses, Apical Alveolar,Abscesses, Apical Dentoalveolar,Abscesses, Periapical,Alveolar Abscesses, Apical,Apical Alveolar Abscess,Apical Alveolar Abscesses,Apical Dentoalveolar Abscess,Apical Dentoalveolar Abscesses,Dentoalveolar Abscesses, Apical,Periapical Abscesses,Periapical Periodontitides, Suppurative,Periodontitides, Suppurative Periapical,Periodontitis, Suppurative Periapical,Suppurative Periapical Periodontitides,Suppurative Periapical Periodontitis
D005145	Face	The anterior portion of the head that includes the skin, muscles, and structures of the forehead, eyes, nose, mouth, cheeks, and jaw.	Faces
D005205	Fascia	Layers of connective tissue of variable thickness. The superficial fascia is found immediately below the skin; the deep fascia invests MUSCLES, nerves, and other organs.
D005491	Focal Infection, Dental	Secondary or systemic infections due to dissemination throughout the body of microorganisms whose primary focus of infection lies in the periodontal tissues.	Dental Focal Infection,Dental Focal Infections,Focal Infections, Dental,Infection, Dental Focal,Infections, Dental Focal
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328	Adult	A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.	Adults