-transparent.png){kind=logo}
BACKGROUND Primary pancreatic paraganglioma is an extremely rare extra-adrenal paraganglioma. METHODS We report a case of primary pancreatic paraganglioma undergoing middle segment pancreatectomy in a 42-year-old woman. Histological examination showed that the tumor was composed of well-defined nests of cuboidal cells separated by vascular fibrous septa, forming the classic Zellballen pattern. The chief cells showed positive staining to neuron-specific enolase, chromogranin A, synaptophysin, and the chief cells were surrounded by S-100 protein-positive sustentacular cells. The patient has remained tumor free for 12 months after surgery. A brief discussion about the histopathological features, clinical behavior, and treatment of primary pancreatic paraganglioma, and review of the relevant literature is presented. CONCLUSIONS Primary pancreatic paraganglioma is a rare clinical entity, its diagnosis mainly depends on histopathological and immunohistochemical examinations. Complete surgical resection is the first choice of treatment and close postoperative follow-up is necessnary.
Shengrong Lin, and
Long Peng, and
Song Huang, and
Yong Li, and
Weidong Xiao
December 2022,
The Journal of international medical research,
Shengrong Lin, and
Long Peng, and
Song Huang, and
Yong Li, and
Weidong Xiao
February 2006,
Clinics (Sao Paulo, Brazil),
Shengrong Lin, and
Long Peng, and
Song Huang, and
Yong Li, and
Weidong Xiao
January 2015,
World journal of gastroenterology,
Shengrong Lin, and
Long Peng, and
Song Huang, and
Yong Li, and
Weidong Xiao
January 2010,
HPB surgery : a world journal of hepatic, pancreatic and biliary surgery,
Shengrong Lin, and
Long Peng, and
Song Huang, and
Yong Li, and
Weidong Xiao
January 2020,
International journal of surgery case reports,
Shengrong Lin, and
Long Peng, and
Song Huang, and
Yong Li, and
Weidong Xiao
August 2015,
Medicine,
Shengrong Lin, and
Long Peng, and
Song Huang, and
Yong Li, and
Weidong Xiao
December 2011,
Quantitative imaging in medicine and surgery,
Shengrong Lin, and
Long Peng, and
Song Huang, and
Yong Li, and
Weidong Xiao
October 2013,
BMC cancer,
Shengrong Lin, and
Long Peng, and
Song Huang, and
Yong Li, and
Weidong Xiao
January 2012,
The Journal of international medical research,
Shengrong Lin, and
Long Peng, and
Song Huang, and
Yong Li, and
Weidong Xiao
January 1988,
Proceedings of the Chinese Academy of Medical Sciences and the Peking Union Medical College = Chung-kuo i hsueh k'o hsueh yuan, Chung-kuo hsieh ho i k'o ta hsueh hsueh pao,
