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Does the preference of peripheral versus central venous access in peripheral blood stem cell collection/yield change stem cell kinetics in autologous stem cell transplantation? 2016
Mehmet Hilmi Dogu, and
Ali Hakan Kaya, and
Ilhami Berber, and
İsmail Sari, and
Emre Tekgündüz, and
Mehmet Ali Erkurt, and
Dicle Iskender, and
Ömur Kayıkçı, and
Irfan Kuku, and
Emin Kaya, and
Ali Keskin, and
Fevzi Altuntaş
Department of Hematology, Faculty of Medicine, Pamukkale University, Denizli, Turkey. Electronic address: mhdogu@yahoo.com.
Central venous access is often used during apheresis procedure in stem cell collection. The aim of the present study was to evaluate whether central or peripheral venous access has an effect on stem cell yield and the kinetics of the procedure and the product in patients undergoing ASCT after high dose therapy. A total of 327 patients were retrospectively reviewed. The use of peripheral venous access for stem cell yield was significantly more frequent in males compared to females (p = 0.005). Total volume of the product was significantly lower in central venous access group (p = 0.046). As being a less invasive procedure, peripheral venous access can be used for stem cell yield in eligible selected patients.
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