Biomaterial Database

False-positive QuantiFERON TB-Gold test due to Mycobacterium gordonae. 2016

Kiran Gajurel, and Aruna K Subramanian

Division of Infectious Diseases, Stanford University School of Medicine, Stanford, CA 94305. Electronic address: kgajurel@stanford.edu.

We report a case of QuantiFERON TB-Gold conversion associated to Mycobacterium gordonae in an elderly male from an assisted living facility without known risk factors for tuberculosis. This knowledge of environmental mycobacteria causing positive quantiferon assays is important to avoid unnecessary treatment of false-positive latent tuberculosis, especially in the absence of well-established positive predictive value of quantiferon conversion.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D009170	Nontuberculous Mycobacteria	So-called atypical species of the genus MYCOBACTERIUM that do not cause tuberculosis. They are also called tuberculoid bacilli, i.e.: M. abscessus, M. buruli, M. chelonae, M. duvalii, M. flavescens, M. fortuitum, M. gilvum, M. gordonae, M. intracellulare (see MYCOBACTERIUM AVIUM COMPLEX;), M. kansasii, M. marinum, M. obuense, M. scrofulaceum, M. szulgai, M. terrae, M. ulcerans, M. xenopi.	Atypical Mycobacteria,Mycobacteria, Atypical,Mycobacterium duvalii,Mycobacterium flavescens,Mycobacterium gilvum,Mycobacterium gordonae,Mycobacterium obuense,Mycobacterium szulgai,Mycobacterium terrae,Mycolicibacter terrae,Mycolicibacterium duvalii,Mycolicibacterium flavescens,Mycolicibacterium gilvum,Mycolicibacterium obuense,Tuberculoid Bacillus,Atypical Mycobacterium,Mycobacterium, Atypical,Non-Tuberculous Mycobacteria,Nontuberculous Mycobacterium
D005189	False Positive Reactions	Positive test results in subjects who do not possess the attribute for which the test is conducted. The labeling of healthy persons as diseased when screening in the detection of disease. (Last, A Dictionary of Epidemiology, 2d ed)	False Positive Reaction,Positive Reaction, False,Positive Reactions, False,Reaction, False Positive,Reactions, False Positive
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000369	Aged, 80 and over	Persons 80 years of age and older.	Oldest Old
D055985	Latent Tuberculosis	The dormant form of TUBERCULOSIS where the person shows no obvious symptoms and no sign of the causative agent (Mycobacterium tuberculosis) in the SPUTUM despite being positive for tuberculosis infection skin test.	Latent Tuberculosis Infection,Infection, Latent Tuberculosis,Infections, Latent Tuberculosis,Latent Tuberculoses,Latent Tuberculosis Infections,Tuberculoses, Latent,Tuberculosis Infection, Latent,Tuberculosis Infections, Latent,Tuberculosis, Latent
D059425	Interferon-gamma Release Tests	The assay of INTERFERON-GAMMA released from lymphocytes after their exposure to a specific test antigen, to check for IMMUNOLOGIC MEMORY resulting from a previous exposure to the antigen. The amount of interferon-gamma released is usually assayed by an ENZYME-LINKED IMMUNOSORBENT ASSAY.	Interferon-gamma Release Assay,Interferon-gamma Release Assays,Assay, Interferon-gamma Release,Assays, Interferon-gamma Release,Interferon gamma Release Assay,Interferon gamma Release Assays,Interferon gamma Release Tests,Interferon-gamma Release Test,Release Assay, Interferon-gamma,Release Assays, Interferon-gamma,Release Test, Interferon-gamma,Release Tests, Interferon-gamma,Test, Interferon-gamma Release,Tests, Interferon-gamma Release
D040561	Assisted Living Facilities	A housing and health care alternative combining independence with personal care. It provides a combination of housing, personalized supportive services and health care designed to meet the needs, both scheduled and unscheduled, of those who need help with activities of daily living. (www.alfa.org)	Assisted Living Facility,Facilities, Assisted Living,Facility, Assisted Living