[Colorectal carcinoma in young adults. Our experience]. 1989

D García Olmo, and E Pellicer Franco, and J Cartagena Sevilla, and G Morales Cuenca, and F Medrano Girón, and J M Pérez Abad, and P Parrilla Paricio

Colorectal cancer usually appears in patients over 60 years-old. However, all the series communicate a small percentage of cases in young patients, ranging from 2 to 10% of the total. We have found important discrepancies between authors who have worked on the possible distinctive characteristics of colorectal cancer of the young over the last decade. This motivated us to examine more closely the clinical, follow-up and prognostic features of colorectal cancerous disease in the young as compared to that occurring in the general population. We analyzed retrospectively the clinical histories of our patients with special reference to the following parameters: sex, diagnostic delay (time from the appearance of the first symptom to diagnosis), index symptom, site, Dukes' grade, type of surgical treatment, complications, recurrence and survival. We found that 4.9% of our patients with colorectal cancer were as old as 40 years. The clinical presentation, tumoral site and Dukes grade were similar in the young adult and in the general population. In spite of the fact that there were no differences in these parameters, in younger patients the surgeon was more aggressive, more often performing a radical operation. Perhaps for this reason, this age group had a higher percentage of complications and recurrences. We found no differences in the 4-year survival or in the time survived after surgery.

UI MeSH Term Description Entries
D008297 Male Males
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D000367 Age Factors Age as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or the effect of a circumstance. It is used with human or animal concepts but should be differentiated from AGING, a physiological process, and TIME FACTORS which refers only to the passage of time. Age Reporting,Age Factor,Factor, Age,Factors, Age
D012189 Retrospective Studies Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons. Retrospective Study,Studies, Retrospective,Study, Retrospective
D015179 Colorectal Neoplasms Tumors or cancer of the COLON or the RECTUM or both. Risk factors for colorectal cancer include chronic ULCERATIVE COLITIS; FAMILIAL POLYPOSIS COLI; exposure to ASBESTOS; and irradiation of the CERVIX UTERI. Colorectal Cancer,Colorectal Carcinoma,Colorectal Tumors,Neoplasms, Colorectal,Cancer, Colorectal,Cancers, Colorectal,Carcinoma, Colorectal,Carcinomas, Colorectal,Colorectal Cancers,Colorectal Carcinomas,Colorectal Neoplasm,Colorectal Tumor,Neoplasm, Colorectal,Tumor, Colorectal,Tumors, Colorectal

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