Biomaterial Database

Acrodermatitis Dysmetabolica in a Child with Cystic Fibrosis. 2016

Sarah Strathie Page, and Rachael Foster

Princess Margaret Hospital, Perth, Western Australia, Australia.

Acrodermatitis dysmetabolica is an umbrella term encompassing the other metabolic causes of an erosive periorificial and acral dermatitis that mimics acrodermatitis enteropathica. Causes include acquired zinc, amino acid, biotin, and fatty acid deficiencies. We present the case of an exclusively breastfed, 2-month-old boy with known cystic fibrosis admitted with failure to thrive and erosive dermatitis. A diagnosis of acrodermatitis dysmetabolica was made when investigations revealed a normal zinc level but low amino acid levels.

UI	MeSH Term	Description	Entries
D007223	Infant	A child between 1 and 23 months of age.	Infants
D008297	Male		Males
D010288	Parenteral Nutrition	The administering of nutrients for assimilation and utilization by a patient who cannot maintain adequate nutrition by enteral feeding alone. Nutrients are administered by a route other than the alimentary canal (e.g., intravenously, subcutaneously).	Intravenous Feeding,Nutrition, Parenteral,Parenteral Feeding,Feeding, Intravenous,Feeding, Parenteral,Feedings, Intravenous,Feedings, Parenteral,Intravenous Feedings,Parenteral Feedings
D002648	Child	A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL.	Children
D003550	Cystic Fibrosis	An autosomal recessive genetic disease of the EXOCRINE GLANDS. It is caused by mutations in the gene encoding the CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR expressed in several organs including the LUNG, the PANCREAS, the BILIARY SYSTEM, and the SWEAT GLANDS. Cystic fibrosis is characterized by epithelial secretory dysfunction associated with ductal obstruction resulting in AIRWAY OBSTRUCTION; chronic RESPIRATORY INFECTIONS; PANCREATIC INSUFFICIENCY; maldigestion; salt depletion; and HEAT PROSTRATION.	Mucoviscidosis,Cystic Fibrosis of Pancreas,Fibrocystic Disease of Pancreas,Pancreatic Cystic Fibrosis,Pulmonary Cystic Fibrosis,Cystic Fibrosis, Pancreatic,Cystic Fibrosis, Pulmonary,Fibrosis, Cystic,Pancreas Fibrocystic Disease,Pancreas Fibrocystic Diseases
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000169	Acrodermatitis	Inflammation involving the skin of the extremities, especially the hands and feet. Several forms are known, some idiopathic and some hereditary. The infantile form is called Gianotti-Crosti syndrome.	Gianotti-Crosti Syndrome,Infantile Papular Acrodermatitis,Acrodermatitis Papulosa Infantum,Acropapulo-Vesicular Syndrome,Erythemato-Vesiculo-Papulous Eruptive Syndrome,Papular Acrodermatitis of Childhood,Papulovesicular Acrolocated Syndrome,Acrodermatitides,Acrodermatitis Papulosa Infantums,Acropapulo Vesicular Syndrome,Acropapulo-Vesicular Syndromes,Childhood Papular Acrodermatitides,Childhood Papular Acrodermatitis,Erythemato Vesiculo Papulous Eruptive Syndrome,Erythemato-Vesiculo-Papulous Eruptive Syndromes,Gianotti Crosti Syndrome,Infantile Papular Acrodermatitides,Papular Acrodermatitides, Infantile,Papular Acrodermatitis, Infantile,Papulovesicular Acrolocated Syndromes,Syndrome, Acropapulo-Vesicular,Syndrome, Erythemato-Vesiculo-Papulous Eruptive,Syndrome, Gianotti-Crosti,Syndromes, Acropapulo-Vesicular,Syndromes, Erythemato-Vesiculo-Papulous Eruptive,Syndromes, Papulovesicular Acrolocated
D000596	Amino Acids	Organic compounds that generally contain an amino (-NH2) and a carboxyl (-COOH) group. Twenty alpha-amino acids are the subunits which are polymerized to form proteins.	Amino Acid,Acid, Amino,Acids, Amino
D015032	Zinc	A metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with ANEMIA, short stature, HYPOGONADISM, impaired WOUND HEALING, and geophagia. It is known by the symbol Zn.