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The contribution of rheological factors to the impedance of blood flow in the umbilical artery as determined by continuous-wave Doppler ultrasound was investigated. Of the 51 pregnancies recruited, six were complicated by pre-eclampsia, 10 by intrauterine growth retardation, 15 by both pre-eclampsia and fetal growth retardation, and there were 20 controls. A significant correlation was demonstrated between both plasma viscosity and gestational age and the resistance index used to characterize the Doppler waveform. Multiple regression analysis demonstrated that changes in plasma viscosity explained 55% of the variance seen in the resistance index and that this was statistically significant. This finding is, however, unlikely to be of clinical significance as whole blood viscosity had an insignificant effect on the impedance in the umbilical artery. We postulate that vascular factors such as the number and calibre of the placental arterioles are a more important determinant of umbilical artery impedance.
S A Steel, and
J M Pearce, and
G Nash, and
B Christopher, and
J Dormandy, and
J M Bland
July 1991,
American journal of perinatology,
S A Steel, and
J M Pearce, and
G Nash, and
B Christopher, and
J Dormandy, and
J M Bland
May 1986,
British journal of obstetrics and gynaecology,
S A Steel, and
J M Pearce, and
G Nash, and
B Christopher, and
J Dormandy, and
J M Bland
January 1988,
Ultrasound in medicine & biology,
S A Steel, and
J M Pearce, and
G Nash, and
B Christopher, and
J Dormandy, and
J M Bland
October 1987,
Seminars in perinatology,
S A Steel, and
J M Pearce, and
G Nash, and
B Christopher, and
J Dormandy, and
J M Bland
December 1987,
Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine,
S A Steel, and
J M Pearce, and
G Nash, and
B Christopher, and
J Dormandy, and
J M Bland
January 1989,
Archives of gynecology and obstetrics,
S A Steel, and
J M Pearce, and
G Nash, and
B Christopher, and
J Dormandy, and
J M Bland
January 1994,
Proceedings. Symposium on Computer Applications in Medical Care,
S A Steel, and
J M Pearce, and
G Nash, and
B Christopher, and
J Dormandy, and
J M Bland
October 1987,
Obstetrics and gynecology,
S A Steel, and
J M Pearce, and
G Nash, and
B Christopher, and
J Dormandy, and
J M Bland
January 1993,
Placenta,
S A Steel, and
J M Pearce, and
G Nash, and
B Christopher, and
J Dormandy, and
J M Bland
December 1987,
Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke,
