Biomaterial Database

Clinical features of human immunodeficiency virus-associated disseminated herpes zoster virus infection--a review of the literature. 1989

P R Cohen, and M E Grossman

Some similarities and several differences in the epidemiological, morphological, therapeutic, and prognostic features of HIV-associated disseminated HZV infection and disseminated HZV infection occurring in HIV-seronegative immunosuppressed patients exist. The severity of the cutaneous disseminated HZV infection, the potential for significant HZV-related morbidity, and the poor prognosis associated with this infection in HIV-seropositive patients, warrants prompt therapeutic intervention. The emergence of acyclovir-resistant HZV infection emphasizes the importance of continued investigation of alternative therapies for individuals with coincident HIV infection.

UI	MeSH Term	Description	Entries
D006562	Herpes Zoster	An acute infectious, usually self-limited, disease believed to represent activation of latent varicella-zoster virus (HERPESVIRUS 3, HUMAN) in those who have been rendered partially immune after a previous attack of CHICKENPOX. It involves the SENSORY GANGLIA and their areas of innervation and is characterized by severe neuralgic pain along the distribution of the affected nerve and crops of clustered vesicles over the area. (From Dorland, 27th ed)	Shingles,Zona,Zoster
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000163	Acquired Immunodeficiency Syndrome	An acquired defect of cellular immunity associated with infection by the human immunodeficiency virus (HIV), a CD4-positive T-lymphocyte count under 200 cells/microliter or less than 14% of total lymphocytes, and increased susceptibility to opportunistic infections and malignant neoplasms. Clinical manifestations also include emaciation (wasting) and dementia. These elements reflect criteria for AIDS as defined by the CDC in 1993.	AIDS,Immunodeficiency Syndrome, Acquired,Immunologic Deficiency Syndrome, Acquired,Acquired Immune Deficiency Syndrome,Acquired Immuno-Deficiency Syndrome,Acquired Immuno Deficiency Syndrome,Acquired Immuno-Deficiency Syndromes,Acquired Immunodeficiency Syndromes,Immuno-Deficiency Syndrome, Acquired,Immuno-Deficiency Syndromes, Acquired,Immunodeficiency Syndromes, Acquired,Syndrome, Acquired Immuno-Deficiency,Syndrome, Acquired Immunodeficiency,Syndromes, Acquired Immuno-Deficiency,Syndromes, Acquired Immunodeficiency