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Using monoclonal antibodies and a dual immunofluorescence technique, we studied the abnormalities of T lymphocyte subsets after human marrow transplantation. T lymphocytes bearing HLA-DR antigen increased both in patients with acute and chronic graft-versus-host disease (GVHD). Parallel to a decrease in CD4+ cells, a CD4+ 2H4+ subset decreased and gradually recovered with time while the percentage of CD4+ 4B4+ cells increased. A significant increase of CD8+ cells observed after marrow transplant corresponded mainly to an increase in CD8+ CD11- cells. Patients with chronic GVHD tended to have a higher proportion of CD8+ CD11+ cells. These results indicate abnormalities of T cell subsets among both CD4+ and CD8+ cells after marrow grafting.
K Matsue, and
S Yasue, and
K Iwabuchi, and
M Ohtsuka, and
M Ueda, and
K Kondo, and
S Shiobara, and
T Mori, and
T Matsuda, and
M Harada
February 1986,
Clinical immunology and immunopathology,
K Matsue, and
S Yasue, and
K Iwabuchi, and
M Ohtsuka, and
M Ueda, and
K Kondo, and
S Shiobara, and
T Mori, and
T Matsuda, and
M Harada
March 1985,
Pathologie-biologie,
K Matsue, and
S Yasue, and
K Iwabuchi, and
M Ohtsuka, and
M Ueda, and
K Kondo, and
S Shiobara, and
T Mori, and
T Matsuda, and
M Harada
September 1982,
Blood,
K Matsue, and
S Yasue, and
K Iwabuchi, and
M Ohtsuka, and
M Ueda, and
K Kondo, and
S Shiobara, and
T Mori, and
T Matsuda, and
M Harada
April 1985,
Transplantation proceedings,
K Matsue, and
S Yasue, and
K Iwabuchi, and
M Ohtsuka, and
M Ueda, and
K Kondo, and
S Shiobara, and
T Mori, and
T Matsuda, and
M Harada
April 1981,
Journal of immunology (Baltimore, Md. : 1950),
K Matsue, and
S Yasue, and
K Iwabuchi, and
M Ohtsuka, and
M Ueda, and
K Kondo, and
S Shiobara, and
T Mori, and
T Matsuda, and
M Harada
January 1985,
The Netherlands journal of medicine,
K Matsue, and
S Yasue, and
K Iwabuchi, and
M Ohtsuka, and
M Ueda, and
K Kondo, and
S Shiobara, and
T Mori, and
T Matsuda, and
M Harada
July 1984,
Rinsho byori. The Japanese journal of clinical pathology,
K Matsue, and
S Yasue, and
K Iwabuchi, and
M Ohtsuka, and
M Ueda, and
K Kondo, and
S Shiobara, and
T Mori, and
T Matsuda, and
M Harada
November 1999,
Transplantation proceedings,
K Matsue, and
S Yasue, and
K Iwabuchi, and
M Ohtsuka, and
M Ueda, and
K Kondo, and
S Shiobara, and
T Mori, and
T Matsuda, and
M Harada
July 1991,
Veterinary immunology and immunopathology,
K Matsue, and
S Yasue, and
K Iwabuchi, and
M Ohtsuka, and
M Ueda, and
K Kondo, and
S Shiobara, and
T Mori, and
T Matsuda, and
M Harada
April 1983,
The British journal of dermatology,
