Biomaterial Database

Is continuous haemofiltration superior to intermittent dialysis and haemofiltration treatment? 1989

H G Sieberth, and H Kierdorf

Medizinische Klinik II, RWTH Aachen, FRG.

1. Mortality in cases of acute renal failure has increased from roughly 30% to roughly 70% in recent decades. 2. The rise paralleled the creation of intensive care units. In such units, more seriously ill patients reach the stage of acute renal failure. Before the advent of intensive care units, these patients died before acute renal failure could occur. 3. From a theoretical viewpoint, continuous haemofiltration (CH) has substantial advantages as opposed to intermittent dialysis and haemofiltration treatment. 4. No clinical proof of the superiority of continuous haemofiltration to the intermittent techniques has yet been provided. 5. In our own patient group, total mortality for acute renal failure patients decreased following adoption of continuous haemofiltration. During a selected period of use of continuous haemofiltration for patients with an unfavourable prognosis, however, the mortality with continuous haemofiltration was higher than that with the intermittent methods.

UI	MeSH Term	Description	Entries
D001783	Blood Flow Velocity	A value equal to the total volume flow divided by the cross-sectional area of the vascular bed.	Blood Flow Velocities,Flow Velocities, Blood,Flow Velocity, Blood,Velocities, Blood Flow,Velocity, Blood Flow
D006440	Hemofiltration	Extracorporeal ULTRAFILTRATION technique without HEMODIALYSIS for treatment of fluid overload and electrolyte disturbances affecting renal, cardiac, or pulmonary function.	Arteriovenous Hemofiltration,Venovenous Hemofiltration,Arteriovenous Hemofiltrations,Hemofiltration, Arteriovenous,Hemofiltration, Venovenous,Hemofiltrations,Venovenous Hemofiltrations
D006493	Heparin	A highly acidic mucopolysaccharide formed of equal parts of sulfated D-glucosamine and D-glucuronic acid with sulfaminic bridges. The molecular weight ranges from six to twenty thousand. Heparin occurs in and is obtained from liver, lung, mast cells, etc., of vertebrates. Its function is unknown, but it is used to prevent blood clotting in vivo and vitro, in the form of many different salts.	Heparinic Acid,alpha-Heparin,Heparin Sodium,Liquaemin,Sodium Heparin,Unfractionated Heparin,Heparin, Sodium,Heparin, Unfractionated,alpha Heparin
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D058186	Acute Kidney Injury	Abrupt reduction in kidney function. Acute kidney injury encompasses the entire spectrum of the syndrome including acute kidney failure; ACUTE KIDNEY TUBULAR NECROSIS; and other less severe conditions.	Acute Kidney Failure,Acute Kidney Insufficiency,Acute Renal Failure,Acute Renal Injury,Acute Renal Insufficiency,Kidney Failure, Acute,Kidney Insufficiency, Acute,Renal Failure, Acute,Renal Insufficiency, Acute,Acute Kidney Failures,Acute Kidney Injuries,Acute Kidney Insufficiencies,Acute Renal Failures,Acute Renal Injuries,Acute Renal Insufficiencies,Kidney Failures, Acute,Kidney Injuries, Acute,Kidney Injury, Acute,Kidney Insufficiencies, Acute,Renal Failures, Acute,Renal Injuries, Acute,Renal Injury, Acute,Renal Insufficiencies, Acute