Effects of lipopolysaccharides on the corrosion behavior of Ni-Cr and Co-Cr alloys. 2016

Weiqiang Yu, and Chao Qian, and Weimin Weng, and Songmei Zhang
Physician-in-charge, Department of Prosthodontics, School of Stomatology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Research Institute of Stomatology, Shanghai, China.

BACKGROUND Lipopolysaccharides (LPS) are constituents of gingival crevicular fluid and may affect the base metal alloys used in metal ceramic crowns. The role of LPS in base metal alloys is currently unknown. OBJECTIVE The purpose of this in vitro study was to evaluate the effects of gram-negative bacterial LPS on the electrochemical behavior of Ni-Cr and Co-Cr alloys. METHODS Alloy specimens were divided into 4 groups according to Escherichia coli LPS concentration (0, 0.15, 15, and 150 μg/mL) in acidic saliva (pH 5). Open circuit potential (OCP) and potentiodynamic polarization behavior were examined using a computer-controlled potentiostat. Metal ions released from the 2 alloys were measured by immersion in LPS-free solution and 150 μg/mL LPS solution and analyzed by inductively coupled plasma atomic emission spectrometry (ICP-AES). Data were evaluated using 1-way ANOVA (α=.05). RESULTS Compared with control groups, medium LPS concentration (15 μg/mL) accelerated Ni-Cr alloy corrosion (P<.05), whereas high LPS concentration (150 μg/mL) accelerated Co-Cr alloy corrosion (P<.05), as determined by OCP, corrosion current density, and polarization resistance parameters. After immersion in high LPS concentrations (150 μg/mL), a slight increase in Ni ion release (P >.05) was observed for the Ni-Cr alloy, while a more significant Co ion release (P<.05) was observed for the Co-Cr alloy. CONCLUSIONS LPS negatively affected the electrochemical behavior of both the Ni-Cr and Co-Cr alloys.

UI MeSH Term Description Entries
D008070 Lipopolysaccharides Lipid-containing polysaccharides which are endotoxins and important group-specific antigens. They are often derived from the cell wall of gram-negative bacteria and induce immunoglobulin secretion. The lipopolysaccharide molecule consists of three parts: LIPID A, core polysaccharide, and O-specific chains (O ANTIGENS). When derived from Escherichia coli, lipopolysaccharides serve as polyclonal B-cell mitogens commonly used in laboratory immunology. (From Dorland, 28th ed) Lipopolysaccharide,Lipoglycans
D008422 Materials Testing The testing of materials and devices, especially those used for PROSTHESES AND IMPLANTS; SUTURES; TISSUE ADHESIVES; etc., for hardness, strength, durability, safety, efficacy, and biocompatibility. Biocompatibility Testing,Biocompatible Materials Testing,Hemocompatibility Testing,Testing, Biocompatible Materials,Testing, Hemocompatible Materials,Hemocompatibility Testings,Hemocompatible Materials Testing,Materials Testing, Biocompatible,Materials Testing, Hemocompatible,Testing, Biocompatibility,Testing, Hemocompatibility,Testing, Materials,Testings, Biocompatibility
D009532 Nickel A trace element with the atomic symbol Ni, atomic number 28, and atomic weight 58.69. It is a cofactor of the enzyme UREASE.
D002858 Chromium Alloys Specific alloys not less than 85% chromium and nickel or cobalt, with traces of either nickel or cobalt, molybdenum, and other substances. They are used in partial dentures, orthopedic implants, etc. Chromium-Cobalt Alloys,Chromium-Nickel Alloys,Cobalt-Chromium Alloys,Nickel-Chromium Alloys,Alloys, Chromium,Alloys, Chromium-Cobalt,Alloys, Chromium-Nickel,Alloys, Cobalt-Chromium,Alloys, Nickel-Chromium,Chromium Cobalt Alloys,Chromium Nickel Alloys,Cobalt Chromium Alloys,Nickel Chromium Alloys
D003343 Corrosion The gradual destruction of a metal or alloy due to oxidation or action of a chemical agent. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed) Corrosions
D004926 Escherichia coli A species of gram-negative, facultatively anaerobic, rod-shaped bacteria (GRAM-NEGATIVE FACULTATIVELY ANAEROBIC RODS) commonly found in the lower part of the intestine of warm-blooded animals. It is usually nonpathogenic, but some strains are known to produce DIARRHEA and pyogenic infections. Pathogenic strains (virotypes) are classified by their specific pathogenic mechanisms such as toxins (ENTEROTOXIGENIC ESCHERICHIA COLI), etc. Alkalescens-Dispar Group,Bacillus coli,Bacterium coli,Bacterium coli commune,Diffusely Adherent Escherichia coli,E coli,EAggEC,Enteroaggregative Escherichia coli,Enterococcus coli,Diffusely Adherent E. coli,Enteroaggregative E. coli,Enteroinvasive E. coli,Enteroinvasive Escherichia coli
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D012464 Saliva, Artificial A solution used for irrigating the mouth in xerostomia and as a substitute for saliva. Artificial Saliva
D016876 Metal Ceramic Alloys The fusion of ceramics (porcelain) to an alloy of two or more metals for use in restorative and prosthodontic dentistry. Examples of metal alloys employed include cobalt-chromium, gold-palladium, gold-platinum-palladium, and nickel-based alloys. Metal Ceramic Restorations,Metallo-Ceramic Alloys,Porcelain-Metal Alloys,Metal Ceramic Alloy,Metallo-Ceramic Alloy,Metalloceramic Alloy,Metalloceramic Alloys,Alloy, Metal Ceramic,Alloy, Metallo-Ceramic,Alloy, Metalloceramic,Alloys, Metal Ceramic,Alloys, Metallo-Ceramic,Alloys, Metalloceramic,Alloys, Porcelain-Metal,Metallo Ceramic Alloy,Metallo Ceramic Alloys,Porcelain Metal Alloys,Restorations, Metal Ceramic

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