[Charles Ledger and the Cinchona]. 1989

P G Janssens

Reading "The life of Charles Ledger", the book written by Gabriele Grammiccia, one notices immediately, what an extraordinary personality Ledger was. He was typically British and belonged to that generation for which, as he wrote himself, "the fact of being a British subject is in itself a reason of pride, including as such a definite obligation to serve the country." This blinding patriotism of even modest British people all over the world, gave the City, as well as the British Empire, a remarkable place in the world trade. The history of Ledger's life, derived from the most authorized sources, is a real adventure novel. At the age of eighteen, he goes to Lima (Peru), in order to find a job. It takes him but a few years to build up his own import-export business. In Tacna, in the very South of Peru, near the Chilean and Bolivian borders (the region where he lived), alpaca wool and quinquina bark are some of the most traded goods. These two products will determine his further life. The principles of his commercial policy were as follows: to buy first quality products, and pack the goods in such a way that they reach the British or European customers in perfect condition, thereby always giving a preferential treatment to the Commonwealth. The quinquina bark trade is hampered by the fact that there is a very great quantity of varieties, each having a different concentration of alkaloids in its bark. To buy the best species, Cinchona calisaya, one needs a perfect knowledge of these trees. The expertise is only to be obtained by visiting the regions where the quinquina tree grows and finding one's way with the help of willing "cascarilleros", the Indians collecting the quinquina bark. During one of his exploration trips, Ledger was fortunate enough to enjoy the service of a Bolivian called Manuel, who faithfully assisted him and his family for years. Together they ranged, at great pains, across every possible region, even the most remote ones; they succeeded in identifying the richest collections of quinquina trees and signing buying contracts on the spot. The most beautiful trees are usually unsuitable for any form of exploitation. In order to understand the special atmosphere that made the solving of the quinquina problems so arduous in the course of time, it seems best to place them in a historical perspective.(ABSTRACT TRUNCATED AT 400 WORDS)

UI MeSH Term Description Entries
D010946 Plants, Medicinal Plants whose roots, leaves, seeds, bark, or other constituent parts possess therapeutic, tonic, purgative, curative or other pharmacologic attributes, when administered to man or animals. Herbs, Medicinal,Medicinal Herbs,Healing Plants,Medicinal Plants,Pharmaceutical Plants,Healing Plant,Herb, Medicinal,Medicinal Herb,Medicinal Plant,Pharmaceutical Plant,Plant, Healing,Plant, Medicinal,Plant, Pharmaceutical,Plants, Healing,Plants, Pharmaceutical
D002929 Cinchona A genus of rubiaceous South American trees that yields the toxic CINCHONA ALKALOIDS from their bark; QUININE; QUINIDINE; chinconine, cinchonidine and others are used to treat MALARIA and CARDIAC ARRHYTHMIAS. Peruvian Bark,Cinchona pubescens,Red Cinchona,Bark, Peruvian,Cinchona, Red,Cinchonas,Cinchonas, Red,Red Cinchonas
D002930 Cinchona Alkaloids Alkaloids extracted from various species of Cinchona. Alkaloids, Cinchona
D004739 England A part of Great Britain within the United Kingdom.
D013020 South America The southern continent of the Western Hemisphere, extending southward from the Colombia-Panama border.
D049672 History, 19th Century Time period from 1801 through 1900 of the common era. 19th Century History,19th Cent. History (Medicine),19th Cent. History of Medicine,19th Cent. Medicine,Historical Events, 19th Century,History of Medicine, 19th Cent.,History, Nineteenth Century,Medical History, 19th Cent.,Medicine, 19th Cent.,19th Cent. Histories (Medicine),19th Century Histories,Cent. Histories, 19th (Medicine),Cent. History, 19th (Medicine),Century Histories, 19th,Century Histories, Nineteenth,Century History, 19th,Century History, Nineteenth,Histories, 19th Cent. (Medicine),Histories, 19th Century,Histories, Nineteenth Century,History, 19th Cent. (Medicine),Nineteenth Century Histories,Nineteenth Century History

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