[Congenital melanotic tumors]. 1989

R Deutschmann, and B Langanke, and G Löwicke

Congenital melanotic tumors are among the very rare tumors of early childhood. Their histogenesis and biological significance are still controversial today. The ideas of an odontogenic origin and of a neuroectodermal pathogenesis of these tumors range among the most frequently advocated hypotheses. Until about 1970 this type of tumor was almost always referred to as benign. Meanwhile there has been a change in the assessment of the character of congenital melanotic tumors. Above all, this is due to the fact that malignant cases have been repeatedly reported since 1970. Apart from an extensive review of the literature, 2 own cases are described which were treated surgically. The histological evaluation of the tumor material supports the assumption that these tumors are of odontogenic origin.

UI MeSH Term Description Entries
D007223 Infant A child between 1 and 23 months of age. Infants
D008441 Maxillary Neoplasms Cancer or tumors of the MAXILLA or upper jaw. Maxillary Neoplasm,Neoplasm, Maxillary,Neoplasms, Maxillary
D008545 Melanoma A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445) Malignant Melanoma,Malignant Melanomas,Melanoma, Malignant,Melanomas,Melanomas, Malignant
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man

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