Biomaterial Database

A chromatographic study of the relative affinities of rat bone and skin collagen alpha1 chains for hydroxyapatite. 1977

C F Nawrot, and D J Campbell

The affinity of a bone collagen alpha1 chain for hydroxyapatite has been compared to a similarly isolated skin component from the same animals. The chain from bone exhibits a higher affinity for the mineral. This enhanced affinity appears to be related to its primary structure, specifically its hydroxylysine moieties.

UI	MeSH Term	Description	Entries
D007842	Lathyrism	A paralytic condition of the legs caused by ingestion of lathyrogens, especially BETA-AMINOPROPIONITRILE or beta-N-oxalyl amino-L-alanine, which are found in the seeds of plants of the genus LATHYRUS.	Neurolathyrism
D008297	Male		Males
D008722	Methods	A series of steps taken in order to conduct research.	Techniques,Methodological Studies,Methodological Study,Procedures,Studies, Methodological,Study, Methodological,Method,Procedure,Technique
D001842	Bone and Bones	A specialized CONNECTIVE TISSUE that is the main constituent of the SKELETON. The principal cellular component of bone is comprised of OSTEOBLASTS; OSTEOCYTES; and OSTEOCLASTS, while FIBRILLAR COLLAGENS and hydroxyapatite crystals form the BONE MATRIX.	Bone Tissue,Bone and Bone,Bone,Bones,Bones and Bone,Bones and Bone Tissue,Bony Apophyses,Bony Apophysis,Condyle,Apophyses, Bony,Apophysis, Bony,Bone Tissues,Condyles,Tissue, Bone,Tissues, Bone
D002845	Chromatography	Techniques used to separate mixtures of substances based on differences in the relative affinities of the substances for mobile and stationary phases. A mobile phase (fluid or gas) passes through a column containing a stationary phase of porous solid or liquid coated on a solid support. Usage is both analytical for small amounts and preparative for bulk amounts.	Chromatographies
D003094	Collagen	A polypeptide substance comprising about one third of the total protein in mammalian organisms. It is the main constituent of SKIN; CONNECTIVE TISSUE; and the organic substance of bones (BONE AND BONES) and teeth (TOOTH).	Avicon,Avitene,Collagen Felt,Collagen Fleece,Collagenfleece,Collastat,Dermodress,Microfibril Collagen Hemostat,Pangen,Zyderm,alpha-Collagen,Collagen Hemostat, Microfibril,alpha Collagen
D006882	Hydroxyapatites	A group of compounds with the general formula M10(PO4)6(OH)2, where M is barium, strontium, or calcium. The compounds are the principal mineral in phosphorite deposits, biological tissue, human bones, and teeth. They are also used as an anticaking agent and polymer catalysts. (Grant & Hackh's Chemical Dictionary, 5th ed)	Hydroxyapatite Derivatives,Derivatives, Hydroxyapatite
D006901	Hydroxylysine	A hydroxylated derivative of the amino acid LYSINE that is present in certain collagens.	(2S,5R)-2,6-Diamino-5-hydroxyhexanoic Acid,2,6-Diamino-5-hydroxyhexanoic Acid,5-Hydroxylysine,Lysine, 5-Hydroxy-,2,6 Diamino 5 hydroxyhexanoic Acid,5 Hydroxylysine,Lysine, 5 Hydroxy
D000367	Age Factors	Age as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or the effect of a circumstance. It is used with human or animal concepts but should be differentiated from AGING, a physiological process, and TIME FACTORS which refers only to the passage of time.	Age Reporting,Age Factor,Factor, Age,Factors, Age
D000629	Aminopropionitrile	Reagent used as an intermediate in the manufacture of beta-alanine and pantothenic acid.	beta-Aminopropionitrile,BAPN,beta Aminopropionitrile