Effect of halothane, enflurane and isoflurane on body temperature during and after surgery. 1989

V Ramachandra, and C Moore, and N Kaur, and F Carli
Department of Anaesthesia, Northwick Park Hospital, Harrow.

The superficial and deep body temperatures of 40 healthy females undergoing total abdominal hysterectomy were measured during surgery and for 4 h afterwards. The patients were allocated randomly to one of five groups and anaesthetized to produce an end-tidal concentration of 1% halothane, 1% enflurane, 2% enflurane, 1% isoflurane or 2% isoflurane. The patients received also 70% nitrous oxide in oxygen and neuromuscular blockade. The theatre temperature was maintained at 22.0 degrees C. There were significant body temperature changes during operation in all groups. The mean (SD) decrease in core temperature over 85 min was approximately 1.1 (0.3) degrees C in the 1% halothane, 2% enflurane and 2% isoflurane groups, and 0.6 (0.4) degrees C in the 1% enflurane and 1% isoflurane groups (P less than 0.05). During the recovery period the 1% halothane, 2% enflurane and 2% isoflurane groups took 2 h to rewarm to preoperative temperatures, and the rate of rewarming during this time was similar for all groups.

UI MeSH Term Description Entries
D007044 Hysterectomy Excision of the uterus. Hysterectomies
D007432 Intraoperative Period The period during a surgical operation. Intraoperative Periods,Period, Intraoperative,Periods, Intraoperative
D007530 Isoflurane A stable, non-explosive inhalation anesthetic, relatively free from significant side effects.
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D011184 Postoperative Period The period following a surgical operation. Period, Postoperative,Periods, Postoperative,Postoperative Periods
D001831 Body Temperature The measure of the level of heat of a human or animal. Organ Temperature,Body Temperatures,Organ Temperatures,Temperature, Body,Temperature, Organ,Temperatures, Body,Temperatures, Organ
D004737 Enflurane An extremely stable inhalation anesthetic that allows rapid adjustments of anesthesia depth with little change in pulse or respiratory rate. Alyrane,Enfran,Enlirane,Ethrane,Etran
D005260 Female Females
D006221 Halothane A nonflammable, halogenated, hydrocarbon anesthetic that provides relatively rapid induction with little or no excitement. Analgesia may not be adequate. NITROUS OXIDE is often given concomitantly. Because halothane may not produce sufficient muscle relaxation, supplemental neuromuscular blocking agents may be required. (From AMA Drug Evaluations Annual, 1994, p178) 1,1,1-Trifluoro-2-Chloro-2-Bromoethane,Fluothane,Ftorotan,Narcotan
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man

Related Publications

V Ramachandra, and C Moore, and N Kaur, and F Carli
August 1992, Masui. The Japanese journal of anesthesiology,
V Ramachandra, and C Moore, and N Kaur, and F Carli
October 1989, South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde,
V Ramachandra, and C Moore, and N Kaur, and F Carli
May 1994, British journal of anaesthesia,
V Ramachandra, and C Moore, and N Kaur, and F Carli
June 1985, Anesthesia and analgesia,
V Ramachandra, and C Moore, and N Kaur, and F Carli
August 1975, British journal of anaesthesia,
V Ramachandra, and C Moore, and N Kaur, and F Carli
January 1985, Pacing and clinical electrophysiology : PACE,
V Ramachandra, and C Moore, and N Kaur, and F Carli
August 1987, British journal of anaesthesia,
V Ramachandra, and C Moore, and N Kaur, and F Carli
January 1989, British journal of anaesthesia,
V Ramachandra, and C Moore, and N Kaur, and F Carli
November 1987, Anesthesiology,
V Ramachandra, and C Moore, and N Kaur, and F Carli
February 1992, Anesthesiology,
Copied contents to your clipboard!