Biomaterial Database

Early soft tissue ingrowth into porous block hydroxyapatite. 1989

T E Butts, and L J Peterson, and C M Allen

Ohio State University, Columbus.

A dog model was used to determine the rate of soft tissue infiltration into porous block hydroxyapatite (PBHA) in order to provide a scientific basis for treatment of exposed implants. Ten mongrel dogs underwent alveolar ridge augmentation with PBHA and were killed at various times up to 21 days. Significant soft tissue ingrowth had occurred by 14 days and was complete by day 21. Bone formation was also seen as early as 14 days.

UI	MeSH Term	Description	Entries
D008334	Mandible	The largest and strongest bone of the FACE constituting the lower jaw. It supports the lower teeth.	Mylohyoid Groove,Mylohyoid Ridge,Groove, Mylohyoid,Grooves, Mylohyoid,Mandibles,Mylohyoid Grooves,Mylohyoid Ridges,Ridge, Mylohyoid,Ridges, Mylohyoid
D004285	Dogs	The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065)	Canis familiaris,Dog
D006097	Granulation Tissue	A vascular connective tissue formed on the surface of a healing wound, ulcer, or inflamed tissue. It consists of new capillaries and an infiltrate containing lymphoid cells, macrophages, and plasma cells.	Granulation Tissues,Tissue, Granulation,Tissues, Granulation
D006882	Hydroxyapatites	A group of compounds with the general formula M10(PO4)6(OH)2, where M is barium, strontium, or calcium. The compounds are the principal mineral in phosphorite deposits, biological tissue, human bones, and teeth. They are also used as an anticaking agent and polymer catalysts. (Grant & Hackh's Chemical Dictionary, 5th ed)	Hydroxyapatite Derivatives,Derivatives, Hydroxyapatite
D000540	Alveolar Ridge Augmentation	Preprosthetic surgery involving rib, cartilage, or iliac crest bone grafts, usually autologous, or synthetic implants for rebuilding the alveolar ridge.	Mandibular Ridge Augmentation,Maxillary Ridge Augmentation,Alveolar Ridge Augmentations,Augmentation, Alveolar Ridge,Augmentation, Mandibular Ridge,Augmentation, Maxillary Ridge,Augmentations, Alveolar Ridge,Augmentations, Mandibular Ridge,Augmentations, Maxillary Ridge,Mandibular Ridge Augmentations,Maxillary Ridge Augmentations,Ridge Augmentation, Alveolar,Ridge Augmentation, Mandibular,Ridge Augmentation, Maxillary,Ridge Augmentations, Alveolar,Ridge Augmentations, Mandibular,Ridge Augmentations, Maxillary
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D014945	Wound Healing	Restoration of integrity to traumatized tissue.	Healing, Wound,Healings, Wound,Wound Healings