Retention deficits produced in monkeys with reversible cold lesions in the prestriate cortex. 1989

C L Martin-Elkins, and P George, and J A Horel
Department of Anatomy and Cell Biology, SUNY Health Science Center, Syracuse 13210.

Cryodes were implanted over the prelunate and fusiform gyri in 4 monkeys. The intention was to block the prestriate projection to the inferotemporal cortex (IT). Cooling this cortex produced deficits that were completely reversed by removing the cold. The deficits appeared in the recall of visual discriminations that were learned prior to the application of the cold, but new discriminations were learned during cooling at the same rate as in control animals. This closely resembles the results of ablation experiments in this same cortex. There was no deficit when cooling this area on a delayed match-to-sample (DMS) task that required the animals to hold visual information over delays of 10 or 45 s. However, performance was close to chance during cooling when the delays were 6 min. With this long delay, when cooling was done separately at sample when the stimulus is received, or at match when the information is recalled, a significant deficit occurred only at match. The results are consistent with the suggestion that this area is involved in retrieval of visual information from long-term memory.

UI MeSH Term Description Entries
D008252 Macaca fascicularis A species of the genus MACACA which typically lives near the coast in tidal creeks and mangrove swamps primarily on the islands of the Malay peninsula. Burmese Long-Tailed Macaque,Crab-Eating Monkey,Cynomolgus Monkey,M. f. aurea,M. fascicularis,Macaca fascicularis aurea,Monkey, Crab-Eating,Monkey, Cynomolgus,Crab-Eating Macaque,Burmese Long Tailed Macaque,Crab Eating Macaque,Crab Eating Monkey,Crab-Eating Macaques,Crab-Eating Monkeys,Cynomolgus Monkeys,Long-Tailed Macaque, Burmese,Macaque, Burmese Long-Tailed,Macaque, Crab-Eating,Monkey, Crab Eating
D008568 Memory Complex mental function having four distinct phases: (1) memorizing or learning, (2) retention, (3) recall, and (4) recognition. Clinically, it is usually subdivided into immediate, recent, and remote memory.
D010364 Pattern Recognition, Visual Mental process to visually perceive a critical number of facts (the pattern), such as characters, shapes, displays, or designs. Recognition, Visual Pattern,Visual Pattern Recognition
D011939 Mental Recall The process whereby a representation of past experience is elicited. Recall, Mental
D012153 Retention, Psychology The persistence to perform a learned behavior (facts or experiences) after an interval has elapsed in which there has been no performance or practice of the behavior. Psychological Retention,Retention (Psychology),Psychology Retention,Retention, Psychological
D001931 Brain Mapping Imaging techniques used to colocalize sites of brain functions or physiological activity with brain structures. Brain Electrical Activity Mapping,Functional Cerebral Localization,Topographic Brain Mapping,Brain Mapping, Topographic,Functional Cerebral Localizations,Mapping, Brain,Mapping, Topographic Brain
D004193 Discrimination Learning Learning that is manifested in the ability to respond differentially to various stimuli. Discriminative Learning,Discrimination Learnings,Discriminative Learnings,Learning, Discrimination,Learning, Discriminative
D004292 Dominance, Cerebral Dominance of one cerebral hemisphere over the other in cerebral functions. Cerebral Dominance,Hemispheric Specialization,Dominances, Cerebral,Specialization, Hemispheric
D005260 Female Females
D005556 Form Perception The sensory discrimination of a pattern, shape, or outline. Contour Perception,Contour Perceptions,Form Perceptions,Perception, Contour,Perception, Form,Perceptions, Contour,Perceptions, Form

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