Biomaterial Database

[Moderate arterial hypertension during its natural course and in drug correction]. 1989

V S Gasilin, and V A Kruglov, and V I Titov, and T I Ushakova

The clinical and morbid anatomy data on 295 patients with arterial hypertension were examined. Two hundred patients had moderate hypertension with the diastolic pressure under 110 mm Hg. Of these, 103 patients had received rauwolfia drugs and 13 patients had been given hypothiazide in addition. Eighty patients who died before 1953 had not received any specific hypotensive drugs. Early hypotensive therapy of moderate hypertension was noted to promote a decrease in arterial blood pressure to normal and to raise the mean lifespan by 8 years. Furthermore the number of fatal brain strokes and myocardial infarctions decreased almost 2-fold.

UI	MeSH Term	Description	Entries
D006973	Hypertension	Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.	Blood Pressure, High,Blood Pressures, High,High Blood Pressure,High Blood Pressures
D011379	Prognosis	A prediction of the probable outcome of a disease based on a individual's condition and the usual course of the disease as seen in similar situations.	Prognostic Factor,Prognostic Factors,Factor, Prognostic,Factors, Prognostic,Prognoses
D001794	Blood Pressure	PRESSURE of the BLOOD on the ARTERIES and other BLOOD VESSELS.	Systolic Pressure,Diastolic Pressure,Pulse Pressure,Pressure, Blood,Pressure, Diastolic,Pressure, Pulse,Pressure, Systolic,Pressures, Systolic
D002423	Cause of Death	Factors which produce cessation of all vital bodily functions. They can be analyzed from an epidemiologic viewpoint.	Causes of Death,Death Cause,Death Causes
D004359	Drug Therapy, Combination	Therapy with two or more separate preparations given for a combined effect.	Combination Chemotherapy,Polychemotherapy,Chemotherapy, Combination,Combination Drug Therapy,Drug Polytherapy,Therapy, Combination Drug,Chemotherapies, Combination,Combination Chemotherapies,Combination Drug Therapies,Drug Polytherapies,Drug Therapies, Combination,Polychemotherapies,Polytherapies, Drug,Polytherapy, Drug,Therapies, Combination Drug
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D006852	Hydrochlorothiazide	A thiazide diuretic often considered the prototypical member of this class. It reduces the reabsorption of electrolytes from the renal tubules. This results in increased excretion of water and electrolytes, including sodium, potassium, chloride, and magnesium. It is used in the treatment of several disorders including edema, hypertension, diabetes insipidus, and hypoparathyroidism.	Dichlothiazide,Dihydrochlorothiazide,Esidrex,Esidrix,HCTZ,HydroDIURIL,Hypothiazide,Oretic,Sectrazide
D046948	Secologanin Tryptamine Alkaloids	Compounds formed by condensation of secologanin with tryptamine resulting in a tetrahydro-beta-carboline which is processed further to a number of bioactive compounds. These are especially found in plants of the APOCYNACEAE; LOGANIACEAE; and RUBIACEAE families.	Monoterpene Indole Alkaloids,Alseroxylon,Monoterpenoid Indole Alkaloids,Rauvolfia Alkaloids,Rauwolfia Alkaloids,Secologanin Indole Alkaloids,Strictosidine Derivatives,Terpenoid Indole Alkaloids,Yohimbans,Alkaloids, Monoterpene Indole,Alkaloids, Monoterpenoid Indole,Alkaloids, Rauvolfia,Alkaloids, Rauwolfia,Alkaloids, Secologanin Indole,Alkaloids, Secologanin Tryptamine,Alkaloids, Terpenoid Indole,Indole Alkaloids, Monoterpene,Indole Alkaloids, Monoterpenoid,Indole Alkaloids, Secologanin,Indole Alkaloids, Terpenoid,Tryptamine Alkaloids, Secologanin