The Chemistry and Bio-Medicinal Significance of Pyrimidines & Condensed Pyrimidines. 2016

K S Jain, and N Arya, and N N Inamdar, and P B Auti, and S A Unawane, and H H Puranik, and M S Sanap, and A D Inamke, and V J Mahale, and C S Prajapati, and C J Shishoo
R.M. Dhariwal Institute of Pharmaceutical Education & Research, Chinchwad, Pune, India. drkishorsjain@gmail.com.

This review discusses the biological and medicinal significance of one of the most important and interesting heterocyclic ring systems, the pyrimidine and its condensed derivatives. Herein, various physiologically important molecules, as well as, therapeutically used drugs having a pyrimidine or condensed pyrimidine system in their chemical structures, have been covered. The chemistry and synthesis of pyrimidines have also been briefly discussed.

UI MeSH Term Description Entries
D011743 Pyrimidines A family of 6-membered heterocyclic compounds occurring in nature in a wide variety of forms. They include several nucleic acid constituents (CYTOSINE; THYMINE; and URACIL) and form the basic structure of the barbiturates.
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man

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