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1. During the two-year period, caries developed at 20% of the target premolar sites. The attack rate for these surfaces was similar in the plaque panel and the other subjects in the study. 2. The microbial composition of plaque samples from caries-free sites and from carious sites before and after radiographic detection of lesions was broadly similar. 3. Numerical domination of particular sites by S mutans before detection of caries can occur, but has only been observed so far in 2 of 15 sites. 4. Pooled date from sites which have developed lesions indicate a rise in the isolation frequency and mean numbers of S. mutans after detection of caries. This trend was particularly obvious in the one subject who developed bilateral lesions by the second examination and in three of four sites where caries was detected at the fourth examination. Similar observations have been made with lactobacilli. 5. In two of 15 instances no isolations of S mutans were made from sites which developed caries. 6. To date, no single species appears to be uniquely associated with the onset of dental caries.
J M Hardie, and
P L Thomson, and
R J South, and
P D Marsh, and
G H Bowden, and
A S McKee, and
E D Fillery, and
G L Slack
January 1974,
Journal of clinical periodontology,
J M Hardie, and
P L Thomson, and
R J South, and
P D Marsh, and
G H Bowden, and
A S McKee, and
E D Fillery, and
G L Slack
February 1974,
Journal of the American Dental Association (1939),
J M Hardie, and
P L Thomson, and
R J South, and
P D Marsh, and
G H Bowden, and
A S McKee, and
E D Fillery, and
G L Slack
February 1977,
British dental journal,
J M Hardie, and
P L Thomson, and
R J South, and
P D Marsh, and
G H Bowden, and
A S McKee, and
E D Fillery, and
G L Slack
March 1969,
Journal of the American Dental Association (1939),
J M Hardie, and
P L Thomson, and
R J South, and
P D Marsh, and
G H Bowden, and
A S McKee, and
E D Fillery, and
G L Slack
February 1986,
Community dentistry and oral epidemiology,
J M Hardie, and
P L Thomson, and
R J South, and
P D Marsh, and
G H Bowden, and
A S McKee, and
E D Fillery, and
G L Slack
June 2015,
Community dentistry and oral epidemiology,
J M Hardie, and
P L Thomson, and
R J South, and
P D Marsh, and
G H Bowden, and
A S McKee, and
E D Fillery, and
G L Slack
December 1990,
Avances en odontoestomatologia,
J M Hardie, and
P L Thomson, and
R J South, and
P D Marsh, and
G H Bowden, and
A S McKee, and
E D Fillery, and
G L Slack
June 1972,
[Hokenfu zasshi] The Japanese journal for public health nurse,
J M Hardie, and
P L Thomson, and
R J South, and
P D Marsh, and
G H Bowden, and
A S McKee, and
E D Fillery, and
G L Slack
January 1998,
Indian journal of pediatrics,
J M Hardie, and
P L Thomson, and
R J South, and
P D Marsh, and
G H Bowden, and
A S McKee, and
E D Fillery, and
G L Slack
January 1974,
Journal of dental research,
