Abnormal development of visual function following intrauterine growth retardation. 1989

O H Stanley, and P J Fleming, and M H Morgan
Department of Child Health, Bristol Maternity Hospital, U.K.

Vernier acuity was measured at 40 weeks post term in 18 infants born with symmetric intrauterine growth retardation (IUGR) and 32 normal (N) infants. Grating acuity was also measured in 12 IUGR and 26 N infants. The mean vernier detection threshold (V.min) was 0.4 octaves higher in the IUGR than in the N infants (P less than 0.04). The mean grating detection threshold (S.min) was 0.2 octaves lower in the IUGR infants (NS). The mean ratio of S.min to V.min was significantly lower in the IUGR infants (1.5 IUGR, 2.7 N, P less than 0.05). V.min was significantly negatively correlated with the head circumference of the IUGR infants at 40 weeks post term. Vernier acuity depends on visual processing at a cortical level. The normal grating acuity in the IUGR infants implies that cortical, rather than optical or retinal factors, underlie the reduced vernier acuity (high V.min). We suggest that the cortical representation of visual space is affected by IUGR.

UI MeSH Term Description Entries
D007230 Infant, Low Birth Weight An infant having a birth weight of 2500 gm. (5.5 lb.) or less but INFANT, VERY LOW BIRTH WEIGHT is available for infants having a birth weight of 1500 grams (3.3 lb.) or less. Low Birth Weight,Low-Birth-Weight Infant,Birth Weight, Low,Birth Weights, Low,Infant, Low-Birth-Weight,Infants, Low-Birth-Weight,Low Birth Weight Infant,Low Birth Weights,Low-Birth-Weight Infants
D007231 Infant, Newborn An infant during the first 28 days after birth. Neonate,Newborns,Infants, Newborn,Neonates,Newborn,Newborn Infant,Newborn Infants
D011247 Pregnancy The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH. Gestation,Pregnancies
D005260 Female Females
D005317 Fetal Growth Retardation Failure of a FETUS to attain expected GROWTH. Growth Retardation, Intrauterine,Intrauterine Growth Retardation,Fetal Growth Restriction,Intrauterine Growth Restriction
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D014796 Visual Perception The selecting and organizing of visual stimuli based on the individual's past experience. Visual Processing,Perception, Visual,Processing, Visual

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