[Use of calcium antagonists in therapy of bronchial asthma]. 1989

V G Alekseev, and A I Sinopal'nikov, and A V Efimov

A study was made of the therapeutic efficacy of calcium antagonists (CA) in the treatment of bronchial asthma. It has been shown that CA, particularly nifedipine and verapamil, do not exert, in the course of an acute drug test, any significant effect on bronchial patency. At the same time CA produce an appreciable preventive effect when administered to bronchial asthma patients with the syndrome of bronchial tree hyperreactivity--cold and post-exercise bronchospasm. Special attention is drawn to CA synergism with inhalation sympathomimetics, which lies in the increase of the duration of the bronchodilating action of the latter ones. The paper provides the data concerned with the effective use of CA in multimodality treatment of the patients with associated bronchial asthma and coronary heart disease.

UI MeSH Term Description Entries
D009543 Nifedipine A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure. Adalat,BAY-a-1040,Bay-1040,Cordipin,Cordipine,Corinfar,Fenigidin,Korinfar,Nifangin,Nifedipine Monohydrochloride,Nifedipine-GTIS,Procardia,Procardia XL,Vascard,BAY a 1040,BAYa1040,Bay 1040,Bay1040,Monohydrochloride, Nifedipine,Nifedipine GTIS
D002121 Calcium Channel Blockers A class of drugs that act by selective inhibition of calcium influx through cellular membranes. Calcium Antagonists, Exogenous,Calcium Blockaders, Exogenous,Calcium Channel Antagonist,Calcium Channel Blocker,Calcium Channel Blocking Drug,Calcium Inhibitors, Exogenous,Channel Blockers, Calcium,Exogenous Calcium Blockader,Exogenous Calcium Inhibitor,Calcium Channel Antagonists,Calcium Channel Blocking Drugs,Exogenous Calcium Antagonists,Exogenous Calcium Blockaders,Exogenous Calcium Inhibitors,Antagonist, Calcium Channel,Antagonists, Calcium Channel,Antagonists, Exogenous Calcium,Blockader, Exogenous Calcium,Blocker, Calcium Channel,Blockers, Calcium Channel,Calcium Blockader, Exogenous,Calcium Inhibitor, Exogenous,Channel Antagonist, Calcium,Channel Blocker, Calcium,Inhibitor, Exogenous Calcium
D004357 Drug Synergism The action of a drug in promoting or enhancing the effectiveness of another drug. Drug Potentiation,Drug Augmentation,Augmentation, Drug,Augmentations, Drug,Drug Augmentations,Drug Potentiations,Drug Synergisms,Potentiation, Drug,Potentiations, Drug,Synergism, Drug,Synergisms, Drug
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D001249 Asthma A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL). Asthma, Bronchial,Bronchial Asthma,Asthmas
D013566 Sympathomimetics Drugs that mimic the effects of stimulating postganglionic adrenergic sympathetic nerves. Included here are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters. Amines, Sympathomimetic,Sympathomimetic,Sympathomimetic Agent,Sympathomimetic Drug,Sympathomimetic Agents,Sympathomimetic Drugs,Sympathomimetic Effect,Sympathomimetic Effects,Agent, Sympathomimetic,Agents, Sympathomimetic,Drug, Sympathomimetic,Drugs, Sympathomimetic,Effect, Sympathomimetic,Effects, Sympathomimetic,Sympathomimetic Amines
D014700 Verapamil A calcium channel blocker that is a class IV anti-arrhythmia agent. Iproveratril,Calan,Cordilox,Dexverapamil,Falicard,Finoptin,Isoptin,Isoptine,Izoptin,Lekoptin,Verapamil Hydrochloride,Hydrochloride, Verapamil

Related Publications

V G Alekseev, and A I Sinopal'nikov, and A V Efimov
April 1987, Harefuah,
V G Alekseev, and A I Sinopal'nikov, and A V Efimov
February 1986, Polskie Archiwum Medycyny Wewnetrznej,
V G Alekseev, and A I Sinopal'nikov, and A V Efimov
January 1986, Polski tygodnik lekarski (Warsaw, Poland : 1960),
V G Alekseev, and A I Sinopal'nikov, and A V Efimov
February 1987, La Clinica terapeutica,
V G Alekseev, and A I Sinopal'nikov, and A V Efimov
October 1954, Hospital (Rio de Janeiro, Brazil),
V G Alekseev, and A I Sinopal'nikov, and A V Efimov
May 1993, The Journal of the Association of Physicians of India,
V G Alekseev, and A I Sinopal'nikov, and A V Efimov
January 1987, Kardiologia polska,
V G Alekseev, and A I Sinopal'nikov, and A V Efimov
March 2001, Drug news & perspectives,
V G Alekseev, and A I Sinopal'nikov, and A V Efimov
January 2006, Terapevticheskii arkhiv,
Copied contents to your clipboard!