Biomaterial Database

Regrowing axons with alternative splicing. 2016

Nicholas J Kramer, and Aaron D Gitler

Department of Genetics and the Neurosciences Graduate Program, Stanford University School of Medicine, Stanford, United States.

The regeneration of axons relies on a previously unknown mechanism that involves the regulation of alternative splicing by CELF proteins.

UI	MeSH Term	Description	Entries
D008322	Mammals	Warm-blooded vertebrate animals belonging to the class Mammalia, including all that possess hair and suckle their young.	Mammalia,Mammal
D012038	Regeneration	The physiological renewal, repair, or replacement of tissue.	Endogenous Regeneration,Regeneration, Endogenous,Regenerations
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D001369	Axons	Nerve fibers that are capable of rapidly conducting impulses away from the neuron cell body.	Axon
D016601	RNA-Binding Proteins	Proteins that bind to RNA molecules. Included here are RIBONUCLEOPROTEINS and other proteins whose function is to bind specifically to RNA.	Double-Stranded RNA-Binding Protein,Double-Stranded RNA-Binding Proteins,ds RNA-Binding Protein,RNA-Binding Protein,ds RNA-Binding Proteins,Double Stranded RNA Binding Protein,Double Stranded RNA Binding Proteins,Protein, Double-Stranded RNA-Binding,Protein, ds RNA-Binding,RNA Binding Protein,RNA Binding Proteins,RNA-Binding Protein, Double-Stranded,RNA-Binding Protein, ds,RNA-Binding Proteins, Double-Stranded,ds RNA Binding Protein
D017173	Caenorhabditis elegans	A species of nematode that is widely used in biological, biochemical, and genetic studies.	Caenorhabditis elegan,elegan, Caenorhabditis
D017398	Alternative Splicing	A process whereby multiple RNA transcripts are generated from a single gene. Alternative splicing involves the splicing together of other possible sets of EXONS during the processing of some, but not all, transcripts of the gene. Thus a particular exon may be connected to any one of several alternative exons to form a mature RNA. The alternative forms of mature MESSENGER RNA produce PROTEIN ISOFORMS in which one part of the isoforms is common while the other parts are different.	RNA Splicing, Alternative,Splicing, Alternative,Alternate Splicing,Nested Transcripts,Alternate Splicings,Alternative RNA Splicing,Alternative RNA Splicings,Alternative Splicings,Nested Transcript,RNA Splicings, Alternative,Splicing, Alternate,Splicing, Alternative RNA,Splicings, Alternate,Splicings, Alternative,Splicings, Alternative RNA,Transcript, Nested,Transcripts, Nested
D050765	Qa-SNARE Proteins	A subfamily of Q-SNARE PROTEINS which occupy the same position as syntaxin 1A in the SNARE complex and which also are most similar to syntaxin 1A in their AMINO ACID SEQUENCE. This subfamily is also known as the syntaxins, although a few so called syntaxins are Qc-SNARES.	Qa-SNAREs,Syntaxin,Syntaxin 10,Syntaxin 10 Protein,Syntaxin 11,Syntaxin 11 Protein,Syntaxin 13,Syntaxin 13 Protein,Syntaxin 17,Syntaxin 17 Protein,Syntaxin 18,Syntaxin 18 Protein,Syntaxin 1A Homologs,Syntaxin 3,Syntaxin 3 Protein,Syntaxin 3A,Syntaxin 3A Protein,Syntaxin 3B,Syntaxin 3B Protein,Syntaxin 3C,Syntaxin 3C Protein,Syntaxin 3D,Syntaxin 3D Protein,Syntaxin 4,Syntaxin 4 Protein,Syntaxin 5,Syntaxin 5 Protein,Syntaxin 6,Syntaxin 6 Protein,Syntaxin 7,Syntaxin 7 Protein,Syntaxin 8,Syntaxin 8 Protein,Syntaxin Protein,Syntaxin Proteins,Syntaxins,Protein, Syntaxin,Protein, Syntaxin 11,Proteins, Syntaxin,Qa SNARE Proteins,Qa SNAREs
D029742	Caenorhabditis elegans Proteins	Proteins from the nematode species CAENORHABDITIS ELEGANS. The proteins from this species are the subject of scientific interest in the area of multicellular organism MORPHOGENESIS.	C elegans Proteins