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Urolithiasis is a frequent disease greatly susceptible to recurrence. The concrements are most frequently caused by metabolical disorders. Metaphylaxis is a comprehensive and long-term regimen which should reduce the rate of recurrence. Non-specific metaphylaxis comprises a general liquid-taking and dietary regimen, specific metaphylaxis is based on the results of metabolical examination and concrement analysis. The authors present the results of comprehensive metaphylaxis in 124 patients (104 with calcium lithiasis and 22 with uric acid lithiasis). The concrement formation decreased from 1.13 of concrement per year prior to treatment, to 0.11 of concrement p. a. during treatment. After almost 5-years of follow-up and treatment, 77% patients had no recurrence, while in 94% it was substantially reduced. Metaphylaxis had no effect in 7 patients (6%). The uric-acid group showed better results than the calcium lithiasis group. The findings are comparable with literary data.
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