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Examination results of corinphar efficacy in the treatment of 25 patients with vibration disease caused by local vibration of mean- and high-frequency range were described. The daily dose of corinphar was 30 mg, the course of treatment lasted 17-21 days. Positive effect was noted in 23 patients. During the treatment course peripheric hemodynamics, microhemocirculation and transcapillary metabolism improved, intensity of lipid peroxidation reactions decreased because of vasodilating, desaggregate and antioxidant impact of the preparation.
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