Predictive factors for residual diplopia after surgical repair in pediatric patients with orbital blowout fracture. 2016

Yun Su, and Qin Shen, and Ming Lin, and Xianqun Fan
Department of Ophthalmology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University, School of Medicine, China.

OBJECTIVE This study aimed to evaluate the clinical prognosis of diplopia and identify factors that are potentially predictive of residual diplopia postoperatively in pediatric patients with orbital blowout fracture. METHODS This was a retrospective study of clinical data from 135 children and adolescents less than 18 years of age who were diagnosed with orbital blowout fractures between January 2008 and June 2014 in the Department of Ophthalmology. A Kaplan-Meier curve and log-rank statistics were used to identify the recovery status from diplopia. Univariate and multivariate Cox proportional hazards analyses were conducted to identify the characteristics associated with residual diplopia. RESULTS Recovery from diplopia was rapid and obvious within 1 year after surgical repair; nearly 80% of the patients were cured of diplopia at that time point, according to the curve. Approximately 85% of the patients would completely recover from diplopia over time, and the remaining patients would most likely have residual diplopia. Multivariate analysis demonstrated that patient age (p < 0.001), the time interval between injury and surgery (p < 0.001) and preoperative muscle swelling (p = 0.028) were factors predictive of residual diplopia. CONCLUSIONS Early intervention in pediatric patients with orbital blowout fracture is recommended to reduce the rate of residual diplopia. Swelling of the ocular muscle and younger age may result in a prolonged recovery time and a lower recovery rate from diplopia after surgery. The recovery from diplopia in pediatric patients appears to be stable 1 year after surgical repair. Therefore, a follow-up time of at least 1 year is recommended for an overall evaluation of residual diplopia in children.

UI MeSH Term Description Entries
D008297 Male Males
D009917 Orbital Fractures Fractures of the bones in the orbit, which include parts of the frontal, ethmoidal, lacrimal, and sphenoid bones and the maxilla and zygoma. Blow Out Fracture,Blow-Out Fractures,Fractures, Blow-Out,Orbital Fracture,Blow Out Fractures,Blow-Out Fracture,Fracture, Blow Out,Fracture, Blow-Out,Fracture, Orbital,Fractures, Blow Out,Fractures, Orbital,Out Fracture, Blow,Out Fractures, Blow
D002648 Child A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL. Children
D004172 Diplopia A visual symptom in which a single object is perceived by the visual cortex as two objects rather than one. Disorders associated with this condition include REFRACTIVE ERRORS; STRABISMUS; OCULOMOTOR NERVE DISEASES; TROCHLEAR NERVE DISEASES; ABDUCENS NERVE DISEASES; and diseases of the BRAIN STEM and OCCIPITAL LOBE. Double Vision,Polyopsia,Diplopia, Cortical,Diplopia, Horizontal,Diplopia, Intermittent,Diplopia, Monocular,Diplopia, Refractive,Diplopia, Unilateral,Diplopia, Vertical,Cortical Diplopia,Cortical Diplopias,Diplopias,Diplopias, Cortical,Diplopias, Horizontal,Diplopias, Intermittent,Diplopias, Monocular,Diplopias, Refractive,Diplopias, Unilateral,Diplopias, Vertical,Horizontal Diplopia,Horizontal Diplopias,Intermittent Diplopia,Intermittent Diplopias,Monocular Diplopia,Monocular Diplopias,Polyopsias,Refractive Diplopia,Refractive Diplopias,Unilateral Diplopia,Unilateral Diplopias,Vertical Diplopia,Vertical Diplopias,Vision, Double
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000293 Adolescent A person 13 to 18 years of age. Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths
D012189 Retrospective Studies Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons. Retrospective Study,Studies, Retrospective,Study, Retrospective

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