Aeroallergen sensitization and allergic disease phenotypes in Asia. 2016

Elizabeth Huiwen Tham, and Alison Joanne Lee, and Hugo Van Bever
Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore and Khoo Teck Puat-National University Children's Medical Institute, National University Health System, Singapore.

Allergic diseases are on the rise in Asia. Aeroallergen exposure is a strong risk factor for sensitization, development and severity of atopic diseases, especially in the Asian paediatric population. Geographical and seasonal variations in aeroallergen sensitization are seen even within Asian countries and changes in aeroallergen sensitization patterns have been observed over time. Some possible reasons include climate change as well as rapid urbanization and improved sanitation which follow socioeconomic development. House dust mite allergy is present in up to 90% of Asian atopic patients, far exceeding that which is seen in Western populations which report prevalences of only 50% to 70%. Pollen and animal dander affect less than 10% of Asian patients as compared to 40-70% of individuals with asthma and allergic rhinitis living in the West, a burden almost equivalent to the dust mite burden in those regions. There is thus a pressing need for preventive measures to reduce dust mite sensitization in Asian children today.

UI MeSH Term Description Entries
D006967 Hypersensitivity Altered reactivity to an antigen, which can result in pathologic reactions upon subsequent exposure to that particular antigen. Allergy,Allergic Reaction,Allergic Reactions,Allergies,Hypersensitivities,Reaction, Allergic,Reactions, Allergic
D007223 Infant A child between 1 and 23 months of age. Infants
D007231 Infant, Newborn An infant during the first 28 days after birth. Neonate,Newborns,Infants, Newborn,Neonates,Newborn,Newborn Infant,Newborn Infants
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D010641 Phenotype The outward appearance of the individual. It is the product of interactions between genes, and between the GENOTYPE and the environment. Phenotypes
D002648 Child A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL. Children
D002675 Child, Preschool A child between the ages of 2 and 5. Children, Preschool,Preschool Child,Preschool Children
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man

Related Publications

Elizabeth Huiwen Tham, and Alison Joanne Lee, and Hugo Van Bever
March 2017, Asian Pacific journal of allergy and immunology,
Elizabeth Huiwen Tham, and Alison Joanne Lee, and Hugo Van Bever
July 2012, The Journal of allergy and clinical immunology,
Elizabeth Huiwen Tham, and Alison Joanne Lee, and Hugo Van Bever
January 2023, Journal of fungi (Basel, Switzerland),
Elizabeth Huiwen Tham, and Alison Joanne Lee, and Hugo Van Bever
June 2018, Asian Pacific journal of allergy and immunology,
Elizabeth Huiwen Tham, and Alison Joanne Lee, and Hugo Van Bever
February 2018, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology,
Elizabeth Huiwen Tham, and Alison Joanne Lee, and Hugo Van Bever
January 2021, Frontiers in allergy,
Elizabeth Huiwen Tham, and Alison Joanne Lee, and Hugo Van Bever
April 2014, The Journal of asthma : official journal of the Association for the Care of Asthma,
Elizabeth Huiwen Tham, and Alison Joanne Lee, and Hugo Van Bever
January 2017, International reviews of immunology,
Elizabeth Huiwen Tham, and Alison Joanne Lee, and Hugo Van Bever
September 2017, Allergy and asthma proceedings,
Elizabeth Huiwen Tham, and Alison Joanne Lee, and Hugo Van Bever
July 2018, Asia Pacific allergy,
Copied contents to your clipboard!