Biomaterial Database

Frequency, intensity, and duration as determinants of P300 from auditory stimuli. 1989

J Polich

Division of Preclinical Neuroscience and Endocrinology, Research Institute of Scripps Clinic, La Jolla, California 92037.

The auditory event-related potential was assessed in two experiments that evaluated the effects of stimulus factors on P300 (P3) component amplitude and latency. The first experiment manipulated the frequency of the target stimuli (500, 1,000, 1,500, and 2,000 Hz) and standard stimuli (250 and 4,000 Hz) in different conditions. Both P3 amplitude and latency were affected by the target and standard tone combinations in specific ways. The second experiment varied the target tone intensity and duration factorially. P3 amplitude was unaffected by these variables, but peak latency was significantly shorter for the loudest and longest target stimuli. The findings indicate that variation in auditory stimulus parameters can produce small but reliable effects for P3 values, which should be considered when results are compared across studies.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D005072	Evoked Potentials, Auditory	The electric response evoked in the CEREBRAL CORTEX by ACOUSTIC STIMULATION or stimulation of the AUDITORY PATHWAYS.	Auditory Evoked Potentials,Auditory Evoked Response,Auditory Evoked Potential,Auditory Evoked Responses,Evoked Potential, Auditory,Evoked Response, Auditory,Evoked Responses, Auditory,Potentials, Auditory Evoked
D005260	Female		Females
D006309	Hearing	The ability or act of sensing and transducing ACOUSTIC STIMULATION to the CENTRAL NERVOUS SYSTEM. It is also called audition.	Audition
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000293	Adolescent	A person 13 to 18 years of age.	Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths
D000328	Adult	A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.	Adults
D001299	Audiometry	The testing of the acuity of the sense of hearing to determine the thresholds of the lowest intensity levels at which an individual can hear a set of tones. The frequencies between 125 and 8000 Hz are used to test air conduction thresholds and the frequencies between 250 and 4000 Hz are used to test bone conduction thresholds.	Audiometries
D001301	Audiometry, Pure-Tone	Measurement of hearing based on the use of pure tones of various frequencies and intensities as auditory stimuli.	Audiometry, Bekesy,Audiometry, Pure Tone,Bekesy Audiometry,Pure-Tone Audiometry
D001307	Auditory Perception	The process whereby auditory stimuli are selected, organized, and interpreted by the organism.	Auditory Processing,Perception, Auditory,Processing, Auditory