The structure of normal human submandibular glands has been studied with the electron microscope. Secretory cells are arranged around a central lumen, and are surrounded by numerous myoepithelial cells, showing tapering process. Intercalated and striated ducts follow secretory units. Striated ducts' cells are characterized by extensive infoldings of the basal plasma membrane, among which numerous mitochondria are aligned. Furthermore, the Authors examine the submandibular gland's innervation.