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A new phenone from the roots of Paeonia suffruticosa Andrews. 2017
Liqin Ding, and
Qingfei Zuo, and
Dandan Li, and
Xinchi Feng, and
Xiumei Gao, and
Feng Zhao, and
Feng Qiu
a Tianjin Key Laboratory of TCM Chemistry and Analysis, Institute of Traditional Chinese Medicine , Tianjin University of Traditional Chinese Medicine , Tianjin , China.
Thirteen phenones were obtained from the 70% ethanol extract of Paeonia suffruticosa Andrews. Their structures were determined on the basis of chemical methods and spectral data. Among them, compound 1 was identified as a new compound, and compounds 5 and 13 were obtained from genus Paeonia for the first time. The inhibitory effects of isolated compounds (1-12) on nitric oxide (NO) production in lipopolysaccharide-activated macrophages were evaluated, and NO production was suppressed significantly by compound 7.
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