Biomaterial Database

[Perthes disease after successfully treated acute juvenile lymphoblastic leukemia]. 1978

D Eckhardt, and E Kircher

The manifestation of Perthes disease after succesfully treated lymphoblastic leukemia is extremely rare. At the first signs of a femoral head necrosis--sonsidering the basic disease--and after cortisone treatment one has to think of a possible femoral head necrosis. It has been observed by several authors after long-term cortison therapy. The case of a 7 year old boy with Perthes disease after acute lymphatic leukemia is demonstrated. After treatment with chemotherapy, cortisone and radiation of the head he was free of pain for 2 years, then the Perthes disease became manifest with a deformed femural head. It could be cured but operation is necessary now or at the latest after termination of growth. In the case there seems to be no connexion between cortisone treatment and the manifestation of Perthes disease. It is more probable that this developed independently of the basic disease and its successful treatment because of the unilateral affection of the hip joint and the interval between treatment of leukemia and manifestion of the first symptoms of Perthes disease.

UI	MeSH Term	Description	Entries
D007873	Legg-Calve-Perthes Disease	A particular type of FEMUR HEAD NECROSIS occurring in children, mainly male, with a course of four years or so.	Coxa Plana,Legg-Perthes Disease,Perthes Disease,Legg-Calve-Perthes Syndrome,Legg-Calvé-Perthes Disease,Legg-Calvé-Perthes Syndrome,Osteochondritis Deformans,Disease, Legg-Calve-Perthes,Disease, Legg-Calvé-Perthes,Disease, Legg-Perthes,Disease, Perthes,Legg Calve Perthes Disease,Legg Calve Perthes Syndrome,Legg Calvé Perthes Disease,Legg Calvé Perthes Syndrome,Legg Perthes Disease,Osteochondritis Deforman,Syndrome, Legg-Calve-Perthes,Syndrome, Legg-Calvé-Perthes
D007945	Leukemia, Lymphoid	Leukemia associated with HYPERPLASIA of the lymphoid tissues and increased numbers of circulating malignant LYMPHOCYTES and lymphoblasts.	Leukemia, Lymphocytic,Lymphocytic Leukemia,Lymphoid Leukemia,Leukemias, Lymphocytic,Leukemias, Lymphoid,Lymphocytic Leukemias,Lymphoid Leukemias
D008297	Male		Males
D010007	Osteochondritis	Inflammation of a bone and its overlaying CARTILAGE.	Meniscitis,Meniscitides,Osteochondritides
D002648	Child	A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL.	Children
D003348	Cortisone	A naturally occurring glucocorticoid that has been used in replacement therapy for ADRENAL INSUFFICIENCY and as an anti-inflammatory agent. Cortisone itself is inactive; it is converted in the liver to the active metabolite HYDROCORTISONE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p726)	17-Hydroxy-3,11,20-trioxopregn-4-en-21-yl acetate,Adreson,Cortisone Acetate,Cortone Acetate
D003937	Diagnosis, Differential	Determination of which one of two or more diseases or conditions a patient is suffering from by systematically comparing and contrasting results of diagnostic measures.	Diagnoses, Differential,Differential Diagnoses,Differential Diagnosis
D005271	Femur Head Necrosis	Aseptic or avascular necrosis of the femoral head. The major types are idiopathic (primary), as a complication of fractures or dislocations, and LEGG-CALVE-PERTHES DISEASE.	Aseptic Necrosis of Femur Head,Avascular Necrosis of Femur Head,Necrosis, Aseptic, of Femur Head,Necrosis, Avascular, of Femur Head,Avascular Necrosis Of Femoral Head, Primary,Femoral Head, Avascular Necrosis Of,Ischemic Necrosis Of Femoral Head,Femur Head Necroses,Head Necrosis, Femur,Necrosis, Femur Head
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man