Biomaterial Database

Human salivary protein interaction with fluoridated synthetic hydroxyapatite. 1978

A Belcourt, and J C Voegel

Adsorption of human salivary protein on synthetic hydroxyapatite after fluoridation of the mineral phase was tested using an experimental system previously described. The salivary protein adsorption on fluoridated apatite was considerably decreased compared to the adsorption obtained with untreated hydroxyapatite. The calcium-precipitable human salivary glycoprotein still seemed to be selectively adsorbed. Liberation of fluoride under the effect of the salivary proteins was also observed. Fluoridation of enamel may decrease pellicle formation with competitive adsorption effect between salivary proteins and fluoride.

UI	MeSH Term	Description	Entries
D005459	Fluorides	Inorganic salts of hydrofluoric acid, HF, in which the fluorine atom is in the -1 oxidation state. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) Sodium and stannous salts are commonly used in dentifrices.	Fluoride
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D006882	Hydroxyapatites	A group of compounds with the general formula M10(PO4)6(OH)2, where M is barium, strontium, or calcium. The compounds are the principal mineral in phosphorite deposits, biological tissue, human bones, and teeth. They are also used as an anticaking agent and polymer catalysts. (Grant & Hackh's Chemical Dictionary, 5th ed)	Hydroxyapatite Derivatives,Derivatives, Hydroxyapatite
D000327	Adsorption	The adhesion of gases, liquids, or dissolved solids onto a surface. It includes adsorptive phenomena of bacteria and viruses onto surfaces as well. ABSORPTION into the substance may follow but not necessarily.	Adsorptions
D012471	Salivary Proteins and Peptides	Proteins and peptides found in SALIVA and the SALIVARY GLANDS. Some salivary proteins such as ALPHA-AMYLASES are enzymes, but their composition varies in different individuals.	Salivary Gland Protein,Salivary Gland Proteins,Salivary Peptide,Salivary Protein,Salivary Proteins,Salivary Peptides,Gland Protein, Salivary,Peptide, Salivary,Protein, Salivary,Protein, Salivary Gland
D044622	Dental Pellicle	A thin protein film on the surface of DENTAL ENAMEL. It is widely believed to result from the selective adsorption of precursor proteins present in SALIVA onto tooth surfaces, and to reduce microbial adherence to the TEETH.	Enamel Pellicle,Salivary Pellicle,Salivary Acquired Pellicle,Acquired Pellicle, Salivary,Pellicle, Dental,Pellicle, Enamel,Pellicle, Salivary,Pellicle, Salivary Acquired