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The occurrence of N-nitroso compounds in kiwam tobacco. 1989

A R Tricker, and R Preussmann
Institute of Toxicology and Chemotherapy, German Cancer Research Center, Heidelberg.

The concentrations of tobacco-specific nitrosamines (TSNA), volatile and non-volatile N-nitroso compounds in kiwam, a fermented Indian tobacco product are presented. Total identified N-nitroso compound concentrations in kiwam ranged from 6.19 to 25.4 mg/kg fresh weight tobacco, the concentration range of TSNA was 5.43-22.2 mg/kg tobacco which accounted for 67-87% of the total identified N-nitroso compound burden. The high concentrations of TSNA found in kiwam tobacco may present a considerable exposure source to carcinogenic N-nitroso compounds for people using this type of tobacco.

UI MeSH Term Description Entries
D007194 India A country in southern Asia, bordering the Arabian Sea and the Bay of Bengal, between Burma and Pakistan. The capitol is New Delhi. Republic of India
D009602 Nitrosamines A class of compounds that contain a -NH2 and a -NO radical. Many members of this group have carcinogenic and mutagenic properties. Nitrosamine
D009603 Nitroso Compounds Organic compounds containing the nitroso (-N Compounds, Nitroso
D010947 Plants, Toxic Plants or plant parts which are harmful to man or other animals. Plants, Poisonous,Plant, Poisonous,Plant, Toxic,Poisonous Plant,Poisonous Plants,Toxic Plant,Toxic Plants
D014026 Nicotiana A plant genus of the family SOLANACEAE. Members contain NICOTINE and other biologically active chemicals; the dried leaves of Nicotiana tabacum are used for SMOKING. Tobacco Plant,Nicotiana tabacum,Plant, Tobacco,Plants, Tobacco,Tobacco Plants
D014030 Tobacco, Smokeless Any product of NICOTIANA TABACUM that is not smoked but is either inhaled through the nose, chewed, or stored in cheek pouches. Chewing Tobacco,Oral Tobacco,Smokeless Tobacco,Snuff,Dipping Tobacco,Gutka,Gutka Tobacco,Mint Snuff,Snus,Chewing Tobaccos,Dipping Tobaccos,Gutka Tobaccos,Gutkas,Snuff, Mint,Tobacco, Chewing,Tobacco, Dipping,Tobacco, Gutka,Tobacco, Oral,Tobaccos, Chewing,Tobaccos, Dipping,Tobaccos, Gutka,Tobaccos, Smokeless

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