Massive Transfusion Protocols: A Survey of Academic Medical Centers in the United States. 2017

Angela B Treml, and Jed B Gorlin, and Richard P Dutton, and Barbara M Scavone
From the *Department of Pathology, the University of Chicago Medicine, Chicago, Illinois; †Memorial Blood Centers, St. Paul, Minnesota; ‡US Anesthesia Partners, Dallas, Texas; and §Department of Anesthesiology, the University of Chicago Medicine, Chicago, Illinois.

Massive transfusion protocols (MTPs) have been adopted in many hospitals, and they may improve outcomes, as well as decrease the number of blood products transfused. However, there are no specific guidelines regarding the number and types of products that should be included in these protocols. MTPs may vary from hospital to hospital. A short, web-based survey was sent to blood bank medical directors at academic institutions to learn details about MTPs. A total of 107 survey requests were sent, and 56 were completed (52% response rate). All who responded had an MTP in place. Nearly all (n = 55, 98.2% [95% CI, 90.6%-99.7%]) base their protocol on delivery of fixed amounts and ratios of blood products, with only a minority incorporating any elements of laboratory-directed therapy. The most common target, red blood cell (RBC):plasma ratio, is 1:1 (n = 39, 69.9% [95% CI, 56.7%-80.1%] of respondents). The majority (n = 36, 64.3% [95% CI, 51.2%-75.6%]) provide 6 or more units of red blood cells in the first MTP packet. One-hundred percent of survey respondents had an MTP in place. Despite a lack of published guidelines regarding MTPs, the survey results demonstrated substantial uniformity in numbers of products and target transfusion ratios.

UI MeSH Term Description Entries
D010818 Practice Patterns, Physicians' Patterns of practice related to diagnosis and treatment as especially influenced by cost of the service requested and provided. Clinical Practice Patterns,Physician's Practice Patterns,Clinical Practice Pattern,Pattern, Clinical Practice,Patterns, Clinical Practice,Practice Pattern, Clinical,Practice Patterns, Clinical,Practice Patterns, Physician's,Prescribing Patterns, Physician,Physician Practice Patterns,Physician Prescribing Pattern,Physician Prescribing Patterns,Physician's Practice Pattern,Physicians' Practice Pattern,Physicians' Practice Patterns,Practice Pattern, Physician's,Practice Pattern, Physicians',Practice Patterns, Physician,Prescribing Pattern, Physician
D001803 Blood Transfusion The introduction of whole blood or blood component directly into the blood stream. (Dorland, 27th ed) Blood Transfusions,Transfusion, Blood,Transfusions, Blood
D002985 Clinical Protocols Precise and detailed plans for the study of a medical or biomedical problem and/or plans for a regimen of therapy. Protocols, Clinical,Research Protocols, Clinical,Treatment Protocols,Clinical Protocol,Clinical Research Protocol,Clinical Research Protocols,Protocol, Clinical,Protocol, Clinical Research,Protocols, Clinical Research,Protocols, Treatment,Research Protocol, Clinical,Treatment Protocol
D003695 Delivery of Health Care The concept concerned with all aspects of providing and distributing health services to a patient population. Delivery of Dental Care,Health Care,Health Care Delivery,Health Care Systems,Community-Based Distribution,Contraceptive Distribution,Delivery of Healthcare,Dental Care Delivery,Distribution, Non-Clinical,Distribution, Nonclinical,Distributional Activities,Healthcare,Healthcare Delivery,Healthcare Systems,Non-Clinical Distribution,Nonclinical Distribution,Activities, Distributional,Activity, Distributional,Care, Health,Community Based Distribution,Community-Based Distributions,Contraceptive Distributions,Deliveries, Healthcare,Delivery, Dental Care,Delivery, Health Care,Delivery, Healthcare,Distribution, Community-Based,Distribution, Contraceptive,Distribution, Non Clinical,Distributional Activity,Distributions, Community-Based,Distributions, Contraceptive,Distributions, Non-Clinical,Distributions, Nonclinical,Health Care System,Healthcare Deliveries,Healthcare System,Non Clinical Distribution,Non-Clinical Distributions,Nonclinical Distributions,System, Health Care,System, Healthcare,Systems, Health Care,Systems, Healthcare
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000046 Academic Medical Centers Medical complexes consisting of medical school, hospitals, clinics, libraries, administrative facilities, etc. Medical Centers, Academic,Medical Centers, University,University Medical Centers,Academic Medical Center,Center, Academic Medical,Center, University Medical,Centers, Academic Medical,Centers, University Medical,Medical Center, Academic,Medical Center, University,University Medical Center
D014481 United States A country in NORTH AMERICA between CANADA and MEXICO.
D016730 Program Development The process of formulating, improving, and expanding educational, managerial, or service-oriented work plans (excluding computer program development). Program Descriptions,Description, Program,Descriptions, Program,Development, Program,Program Description
D017410 Practice Guidelines as Topic Works about directions or principles presenting current or future rules of policy for assisting health care practitioners in patient care decisions regarding diagnosis, therapy, or related clinical circumstances. The guidelines may be developed by government agencies at any level, institutions, professional societies, governing boards, or by the convening of expert panels. The guidelines form a basis for the evaluation of all aspects of health care and delivery. Clinical Guidelines as Topic,Best Practices,Best Practice
D019538 Health Care Surveys Statistical measures of utilization and other aspects of the provision of health care services including hospitalization and ambulatory care. Healthcare Surveys,National Ambulatory Medical Care Survey,National Hospital Discharge Survey,Care Survey, Health,Care Surveys, Health,Health Care Survey,Healthcare Survey,Survey, Health Care,Survey, Healthcare,Surveys, Health Care,Surveys, Healthcare

Related Publications

Angela B Treml, and Jed B Gorlin, and Richard P Dutton, and Barbara M Scavone
July 2010, Transfusion,
Angela B Treml, and Jed B Gorlin, and Richard P Dutton, and Barbara M Scavone
August 2002, Anesthesia and analgesia,
Angela B Treml, and Jed B Gorlin, and Richard P Dutton, and Barbara M Scavone
April 2023, Optometry and vision science : official publication of the American Academy of Optometry,
Angela B Treml, and Jed B Gorlin, and Richard P Dutton, and Barbara M Scavone
December 1988, Human pathology,
Angela B Treml, and Jed B Gorlin, and Richard P Dutton, and Barbara M Scavone
February 2010, PLoS medicine,
Angela B Treml, and Jed B Gorlin, and Richard P Dutton, and Barbara M Scavone
April 2017, Anesthesia and analgesia,
Angela B Treml, and Jed B Gorlin, and Richard P Dutton, and Barbara M Scavone
November 2013, Hospital pharmacy,
Angela B Treml, and Jed B Gorlin, and Richard P Dutton, and Barbara M Scavone
January 2017, Anesthesia and analgesia,
Angela B Treml, and Jed B Gorlin, and Richard P Dutton, and Barbara M Scavone
September 2011, Academic medicine : journal of the Association of American Medical Colleges,
Angela B Treml, and Jed B Gorlin, and Richard P Dutton, and Barbara M Scavone
January 1973, Acta anaesthesiologica Scandinavica. Supplementum,
Copied contents to your clipboard!