BIOMAT Database Logo BIOMAT Database Logo

Creatine Monohydrate Supplementation Does Not Augment Fitness, Performance, or Body Composition Adaptations in Response to Four Weeks of High-Intensity Interval Training in Young Females. 2017

Scott C Forbes, and Nathan Sletten, and Cody Durrer, and Étienne Myette-Côté, and D Candow, and Jonathan P Little

High-intensity interval training (HIIT) has been shown to improve cardiorespiratory fitness, performance, body composition, and insulin sensitivity. Creatine (Cr) supplementation may augment responses to HIIT, leading to even greater physiological adaptations. The purpose of this study was to determine the effects of 4 weeks of HIIT (three sessions/week) combined with Cr supplementation in recreationally active females. Seventeen females (age = 23 ± 4 yrs; BMI = 23.4 ± 2.4) were randomly assigned to either Cr (Cr; 0.3 g・kg-1・d-1 for 5 d followed by 0.1 g・kg-1・d-1 for 23 days; n = 9) or placebo (PLA; n = 8). Before and after the intervention, VO2peak, ventilatory threshold (VT), time-trial performance, lean body mass and fat mass, and insulin sensitivity were assessed. HIIT improved VO2peak (Cr = +10.2%; PLA = +8.8%), VT (Cr = +12.7%; PLA = +9.9%), and time-trial performance (Cr = -11.5%; PLA = -11.6%) with no differences between groups (time main effects, all p < .001). There were no changes over time for fat mass (Cr = -0.3%; PLA = +4.3%), whole-body lean mass (Cr = +0.5%; PLA = -0.9%), or insulin resistance (Cr = +3.9%; PLA = +18.7%). In conclusion, HIIT is an effective way to improve cardiorespiratory fitness, VT, and time-trial performance. The addition of Cr to HIIT did not augment improvements in cardiorespiratory fitness, performance or body composition in recreationally active females.

UI MeSH Term Description Entries
D007333 Insulin Resistance Diminished effectiveness of INSULIN in lowering blood sugar levels: requiring the use of 200 units or more of insulin per day to prevent HYPERGLYCEMIA or KETOSIS. Insulin Sensitivity,Resistance, Insulin,Sensitivity, Insulin
D010101 Oxygen Consumption The rate at which oxygen is used by a tissue; microliters of oxygen STPD used per milligram of tissue per hour; the rate at which oxygen enters the blood from alveolar gas, equal in the steady state to the consumption of oxygen by tissue metabolism throughout the body. (Stedman, 25th ed, p346) Consumption, Oxygen,Consumptions, Oxygen,Oxygen Consumptions
D001823 Body Composition The relative amounts of various components in the body, such as percentage of body fat. Body Compositions,Composition, Body,Compositions, Body
D003401 Creatine An amino acid that occurs in vertebrate tissues and in urine. In muscle tissue, creatine generally occurs as phosphocreatine. Creatine is excreted as CREATININE in the urine.
D005080 Exercise Test Controlled physical activity which is performed in order to allow assessment of physiological functions, particularly cardiovascular and pulmonary, but also aerobic capacity. Maximal (most intense) exercise is usually required but submaximal exercise is also used. Arm Ergometry Test,Bicycle Ergometry Test,Cardiopulmonary Exercise Testing,Exercise Testing,Step Test,Stress Test,Treadmill Test,Cardiopulmonary Exercise Test,EuroFit Tests,Eurofit Test Battery,European Fitness Testing Battery,Fitness Testing,Physical Fitness Testing,Arm Ergometry Tests,Bicycle Ergometry Tests,Cardiopulmonary Exercise Tests,Ergometry Test, Arm,Ergometry Test, Bicycle,Ergometry Tests, Arm,Ergometry Tests, Bicycle,EuroFit Test,Eurofit Test Batteries,Exercise Test, Cardiopulmonary,Exercise Testing, Cardiopulmonary,Exercise Tests,Exercise Tests, Cardiopulmonary,Fitness Testing, Physical,Fitness Testings,Step Tests,Stress Tests,Test Battery, Eurofit,Test, Arm Ergometry,Test, Bicycle Ergometry,Test, Cardiopulmonary Exercise,Test, EuroFit,Test, Exercise,Test, Step,Test, Stress,Test, Treadmill,Testing, Cardiopulmonary Exercise,Testing, Exercise,Testing, Fitness,Testing, Physical Fitness,Tests, Arm Ergometry,Tests, Bicycle Ergometry,Tests, Cardiopulmonary Exercise,Tests, EuroFit,Tests, Exercise,Tests, Step,Tests, Stress,Tests, Treadmill,Treadmill Tests
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000072599 Cardiorespiratory Fitness A measure of the functional capabilities of the heart, lungs and muscles, relative to the demands of specific exercise routines such as running or cycling. Fitness, Cardiorespiratory
D000072696 High-Intensity Interval Training A cardiovascular exercise strategy with alternating short periods of intense anaerobic exercise with less-intense recovery periods. High-Intensity Intermittent Exercise,Sprint Interval Training,Exercise, High-Intensity Intermittent,Exercises, High-Intensity Intermittent,High Intensity Interval Training,High-Intensity Intermittent Exercises,High-Intensity Interval Trainings,Interval Training, High-Intensity,Interval Trainings, High-Intensity,Sprint Interval Trainings,Training, High-Intensity Interval,Trainings, High-Intensity Interval
D000222 Adaptation, Physiological The non-genetic biological changes of an organism in response to challenges in its ENVIRONMENT. Adaptation, Physiologic,Adaptations, Physiologic,Adaptations, Physiological,Adaptive Plasticity,Phenotypic Plasticity,Physiological Adaptation,Physiologic Adaptation,Physiologic Adaptations,Physiological Adaptations,Plasticity, Adaptive,Plasticity, Phenotypic

Related Publications

Scott C Forbes, and Nathan Sletten, and Cody Durrer, and Étienne Myette-Côté, and D Candow, and Jonathan P Little
Whole-body cryotherapy does not augment adaptations to high-intensity interval training.
August 2019, Scientific reports,
Scott C Forbes, and Nathan Sletten, and Cody Durrer, and Étienne Myette-Côté, and D Candow, and Jonathan P Little
Resveratrol supplementation does not augment performance adaptations or fibre-type-specific responses to high-intensity interval training in humans.
November 2014, Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme,
Scott C Forbes, and Nathan Sletten, and Cody Durrer, and Étienne Myette-Côté, and D Candow, and Jonathan P Little
A buffered form of creatine does not promote greater changes in muscle creatine content, body composition, or training adaptations than creatine monohydrate.
September 2012, Journal of the International Society of Sports Nutrition,
Scott C Forbes, and Nathan Sletten, and Cody Durrer, and Étienne Myette-Côté, and D Candow, and Jonathan P Little
Creatine monohydrate supplementation enhances high-intensity exercise performance in males and females.
December 2000, International journal of sport nutrition and exercise metabolism,
Scott C Forbes, and Nathan Sletten, and Cody Durrer, and Étienne Myette-Côté, and D Candow, and Jonathan P Little
Altering the rest interval during high-intensity interval training does not affect muscle or performance adaptations.
February 2013, Experimental physiology,
Scott C Forbes, and Nathan Sletten, and Cody Durrer, and Étienne Myette-Côté, and D Candow, and Jonathan P Little
The effects of four weeks of creatine supplementation and high-intensity interval training on cardiorespiratory fitness: a randomized controlled trial.
November 2009, Journal of the International Society of Sports Nutrition,
Scott C Forbes, and Nathan Sletten, and Cody Durrer, and Étienne Myette-Côté, and D Candow, and Jonathan P Little
Neural, metabolic, and performance adaptations to four weeks of high intensity sprint-interval training in trained cyclists.
February 2004, International journal of sports medicine,
Scott C Forbes, and Nathan Sletten, and Cody Durrer, and Étienne Myette-Côté, and D Candow, and Jonathan P Little
Five Weeks of Aquatic-Calisthenic High Intensity Interval Training Improves Cardiorespiratory Fitness and Body Composition in Sedentary Young Adults.
March 2020, Journal of sports science & medicine,
Scott C Forbes, and Nathan Sletten, and Cody Durrer, and Étienne Myette-Côté, and D Candow, and Jonathan P Little
Protein Supplementation Does Not Augment Adaptations to Endurance Exercise Training.
October 2019, Medicine and science in sports and exercise,
Scott C Forbes, and Nathan Sletten, and Cody Durrer, and Étienne Myette-Côté, and D Candow, and Jonathan P Little
β-Alanine Supplementation Does Not Augment the Skeletal Muscle Adaptive Response to 6 Weeks of Sprint Interval Training.
December 2015, International journal of sport nutrition and exercise metabolism,
Copied contents to your clipboard!