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Comparative results of chemo- and chemoimmunotherapy with Soviet strain of BCG vaccine in children with acute leukemia are presented. The immunotherapeutical regimen includes 20 intracutaneous injections of 0.1 mg BCG vaccine given weekly during 5--6 months with subsequent 5--6 months intervals simultaneously with maintenance chemotherapy. In the control group children were only given conventional chemotherapy. The median duration of remission and survival in patients who had received BCG chemoimmunotherapy was 25.2 +/- 1.5 and 32.3 +/- 1.2 months respectively. In the group of patients with chemotherapy alone--13.2 +/- 0.9 and 21.8 +/- 1.1 months respectively (p less than 0.01). The best results were obtained in children who had received before BCG immunotherapy neuroleukemia prophylactic treatment.
V M Bergolz, and
N S Kisljak, and
V S Eremeev, and
A G Rumjanzev, and
G V Akimova, and
A M Molochkina, and
S G Osipov
January 1980,
Sovetskaia meditsina,
V M Bergolz, and
N S Kisljak, and
V S Eremeev, and
A G Rumjanzev, and
G V Akimova, and
A M Molochkina, and
S G Osipov
May 1978,
Nihon rinsho. Japanese journal of clinical medicine,
V M Bergolz, and
N S Kisljak, and
V S Eremeev, and
A G Rumjanzev, and
G V Akimova, and
A M Molochkina, and
S G Osipov
June 1977,
Problemy gematologii i perelivaniia krovi,
V M Bergolz, and
N S Kisljak, and
V S Eremeev, and
A G Rumjanzev, and
G V Akimova, and
A M Molochkina, and
S G Osipov
July 1977,
Israel journal of medical sciences,
V M Bergolz, and
N S Kisljak, and
V S Eremeev, and
A G Rumjanzev, and
G V Akimova, and
A M Molochkina, and
S G Osipov
January 2012,
Blood reviews,
V M Bergolz, and
N S Kisljak, and
V S Eremeev, and
A G Rumjanzev, and
G V Akimova, and
A M Molochkina, and
S G Osipov
March 1981,
Cancer,
V M Bergolz, and
N S Kisljak, and
V S Eremeev, and
A G Rumjanzev, and
G V Akimova, and
A M Molochkina, and
S G Osipov
April 1981,
The Tokai journal of experimental and clinical medicine,
V M Bergolz, and
N S Kisljak, and
V S Eremeev, and
A G Rumjanzev, and
G V Akimova, and
A M Molochkina, and
S G Osipov
January 1981,
Archivum immunologiae et therapiae experimentalis,
V M Bergolz, and
N S Kisljak, and
V S Eremeev, and
A G Rumjanzev, and
G V Akimova, and
A M Molochkina, and
S G Osipov
January 1988,
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie,
V M Bergolz, and
N S Kisljak, and
V S Eremeev, and
A G Rumjanzev, and
G V Akimova, and
A M Molochkina, and
S G Osipov
October 1976,
Cancer,
