BIOMAT Database Logo BIOMAT Database Logo

Leukemic infiltration presenting as myocardial hypertrophy after complete remission of acute myeloid leukemia. 2017

Mi-Hyang Jung, and Youn-Ho Lee, and Kyo-Young Lee, and Hae Ok Jung, and Ho-Joong Youn
Cardiovascular Center, College of Medicine, Seoul St. Mary's Hospital, The Catholic University of Korea, Seoul, Korea.

Here, we report a rare case of isolated leukemic infiltrate of the myocardium (extramedullary involvement) presenting as restrictive cardiomyopathy in a patient in complete remission of acute myeloid leukemia. It was evaluated with multimodality imaging studies (echocardiography and cardiac MRI) and further confirmed by pathology. The present case highlights the importance of maintaining a high degree of clinical suspicion when evaluating patients with progressive ventricular hypertrophy of unknown cause, including recognition of the potential involvement by recurrent hematologic malignancy.

UI MeSH Term Description Entries
D006984 Hypertrophy General increase in bulk of a part or organ due to CELL ENLARGEMENT and accumulation of FLUIDS AND SECRETIONS, not due to tumor formation, nor to an increase in the number of cells (HYPERPLASIA). Hypertrophies
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D009206 Myocardium The muscle tissue of the HEART. It is composed of striated, involuntary muscle cells (MYOCYTES, CARDIAC) connected to form the contractile pump to generate blood flow. Muscle, Cardiac,Muscle, Heart,Cardiac Muscle,Myocardia,Cardiac Muscles,Heart Muscle,Heart Muscles,Muscles, Cardiac,Muscles, Heart
D012074 Remission Induction Therapeutic act or process that initiates a response to a complete or partial remission level. Induction of Remission,Induction, Remission,Inductions, Remission,Remission Inductions
D002313 Cardiomyopathy, Restrictive A form of CARDIAC MUSCLE disease in which the ventricular walls are excessively rigid, impeding ventricular filling. It is marked by reduced diastolic volume of either or both ventricles but normal or nearly normal systolic function. It may be idiopathic or associated with other diseases (ENDOMYOCARDIAL FIBROSIS or AMYLOIDOSIS) causing interstitial fibrosis. Familial Restrictive Cardiomyopathy,Cardiomyopathies, Restrictive,Restrictive Cardiomyopathies,Restrictive Cardiomyopathy
D004452 Echocardiography Ultrasonic recording of the size, motion, and composition of the heart and surrounding tissues. The standard approach is transthoracic. Echocardiography, Contrast,Echocardiography, Cross-Sectional,Echocardiography, M-Mode,Echocardiography, Transthoracic,Echocardiography, Two-Dimensional,Transthoracic Echocardiography,2-D Echocardiography,2D Echocardiography,Contrast Echocardiography,Cross-Sectional Echocardiography,Echocardiography, 2-D,Echocardiography, 2D,M-Mode Echocardiography,Two-Dimensional Echocardiography,2 D Echocardiography,Cross Sectional Echocardiography,Echocardiography, 2 D,Echocardiography, Cross Sectional,Echocardiography, M Mode,Echocardiography, Two Dimensional,M Mode Echocardiography,Two Dimensional Echocardiography
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D015470 Leukemia, Myeloid, Acute Clonal expansion of myeloid blasts in bone marrow, blood, and other tissue. Myeloid leukemias develop from changes in cells that normally produce NEUTROPHILS; BASOPHILS; EOSINOPHILS; and MONOCYTES. Leukemia, Myelogenous, Acute,Leukemia, Nonlymphocytic, Acute,Myeloid Leukemia, Acute,Nonlymphocytic Leukemia, Acute,ANLL,Acute Myelogenous Leukemia,Acute Myeloid Leukemia,Acute Myeloid Leukemia with Maturation,Acute Myeloid Leukemia without Maturation,Leukemia, Acute Myelogenous,Leukemia, Acute Myeloid,Leukemia, Myeloblastic, Acute,Leukemia, Myelocytic, Acute,Leukemia, Myeloid, Acute, M1,Leukemia, Myeloid, Acute, M2,Leukemia, Nonlymphoblastic, Acute,Myeloblastic Leukemia, Acute,Myelocytic Leukemia, Acute,Myelogenous Leukemia, Acute,Myeloid Leukemia, Acute, M1,Myeloid Leukemia, Acute, M2,Nonlymphoblastic Leukemia, Acute,Acute Myeloblastic Leukemia,Acute Myeloblastic Leukemias,Acute Myelocytic Leukemia,Acute Myelocytic Leukemias,Acute Myelogenous Leukemias,Acute Myeloid Leukemias,Acute Nonlymphoblastic Leukemia,Acute Nonlymphoblastic Leukemias,Acute Nonlymphocytic Leukemia,Acute Nonlymphocytic Leukemias,Leukemia, Acute Myeloblastic,Leukemia, Acute Myelocytic,Leukemia, Acute Nonlymphoblastic,Leukemia, Acute Nonlymphocytic,Leukemias, Acute Myeloblastic,Leukemias, Acute Myelocytic,Leukemias, Acute Myelogenous,Leukemias, Acute Myeloid,Leukemias, Acute Nonlymphoblastic,Leukemias, Acute Nonlymphocytic,Myeloblastic Leukemias, Acute,Myelocytic Leukemias, Acute,Myelogenous Leukemias, Acute,Myeloid Leukemias, Acute,Nonlymphoblastic Leukemias, Acute,Nonlymphocytic Leukemias, Acute
D017254 Leukemic Infiltration A pathologic change in leukemia in which leukemic cells permeate various organs at any stage of the disease. All types of leukemia show various degrees of infiltration, depending upon the type of leukemia. The degree of infiltration may vary from site to site. The liver and spleen are common sites of infiltration, the greatest appearing in myelocytic leukemia, but infiltration is seen also in the granulocytic and lymphocytic types. The kidney is also a common site and of the gastrointestinal system, the stomach and ileum are commonly involved. In lymphocytic leukemia the skin is often infiltrated. The central nervous system too is a common site. Infiltration, Leukemic,Infiltrations, Leukemic,Leukemic Infiltrations

Related Publications

Mi-Hyang Jung, and Youn-Ho Lee, and Kyo-Young Lee, and Hae Ok Jung, and Ho-Joong Youn
Myeloid Sarcoma After «Complete» Remission of Acute Myeloid Leukemia.
December 2023, Actas dermo-sifiliograficas,
Mi-Hyang Jung, and Youn-Ho Lee, and Kyo-Young Lee, and Hae Ok Jung, and Ho-Joong Youn
[Detection of residual leukemic cells after complete remission of patients with acute myeloid leukemia].
December 2004, Zhongguo shi yan xue ye xue za zhi,
Mi-Hyang Jung, and Youn-Ho Lee, and Kyo-Young Lee, and Hae Ok Jung, and Ho-Joong Youn
[Acute myeloid leukemia with complete remission].
September 1950, Nordisk medicin,
Mi-Hyang Jung, and Youn-Ho Lee, and Kyo-Young Lee, and Hae Ok Jung, and Ho-Joong Youn
Gingival leukemic infiltration as the first manifestation of acute myeloid leukemia.
May 2018, Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry,
Mi-Hyang Jung, and Youn-Ho Lee, and Kyo-Young Lee, and Hae Ok Jung, and Ho-Joong Youn
Gingival leukemic infiltration as the first manifestation of acute myeloid leukemia.
September 2010, Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery,
Mi-Hyang Jung, and Youn-Ho Lee, and Kyo-Young Lee, and Hae Ok Jung, and Ho-Joong Youn
Immunotherapy with BCG and leukemic blast cells during complete remission of acute myeloid leukemia.
October 1977, Haematologica,
Mi-Hyang Jung, and Youn-Ho Lee, and Kyo-Young Lee, and Hae Ok Jung, and Ho-Joong Youn
Acute myeloid leukemia with hepatic infiltration presenting as obstructive jaundice.
January 2021, Leukemia research reports,
Mi-Hyang Jung, and Youn-Ho Lee, and Kyo-Young Lee, and Hae Ok Jung, and Ho-Joong Youn
[Recurrence of acute myeloid leukemia after 13 years of complete remission].
August 1984, [Rinsho ketsueki] The Japanese journal of clinical hematology,
Mi-Hyang Jung, and Youn-Ho Lee, and Kyo-Young Lee, and Hae Ok Jung, and Ho-Joong Youn
[Leukemic retinal infiltrate in acute myeloid leukemia in remission].
March 1984, Deutsche medizinische Wochenschrift (1946),
Mi-Hyang Jung, and Youn-Ho Lee, and Kyo-Young Lee, and Hae Ok Jung, and Ho-Joong Youn
Isolated choroidal leukemic infiltration during complete remission.
July 1997, American journal of hematology,
Copied contents to your clipboard!