Clinical outcomes of endoscopic surveillance for gastric ulcers in populations with a high prevalence of gastric cancer. 2016

Young Bae Lee, and Jaeho Han, and Jeong Hyeon Cho, and Hong Sub Lee
Department of Internal Medicine, Seonam University College of Medicine, Myongji Hospital, Goyang, Korea. epoch0123@naver.com.

OBJECTIVE Although surveillance endoscopy is recommended after the treatment of a benign gastric ulcer in Korea, improved survival, secondary to an endoscopic follow-up strategy, is controversial. Thus, the aim of this study was to understand the results of gastric ulcer surveillance endoscopy and to individualize surveillance endoscopy by analyzing known risk factors for gastric cancer. METHODS In total, 599 (M:F=424:175, median age=55.4 years) patients who were diagnosed with a gastric ulcer and who underwent follow-up endoscopy between January 2003 and August 2014 were retrospectively enrolled in this study. The final results and risk factors of follow-up endoscopy were analyzed. RESULTS Multivariate analysis of the data between the benign and malignant ulcer groups (benign: malignant=575:24) showed that an elevated border and irregular margins, among other risk factors, were significant indicators of malignancy (p<0.05). Of the 599 patients, 15 (2.5%) were histologically malignant based on the first biopsy results. Nine (1.5%) patients had malignant ulcers on surveillance endoscopy, and all nine were found to have atypia or dysplasia on the first biopsy. Eight of the nine patients had malignant endoscopic features. CONCLUSIONS Surveillance endoscopy for gastric ulcers may be unnecessary, except in cases of malignant and pre-malignant endoscopic features on the initial endoscopy.

UI MeSH Term Description Entries
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D011159 Population Surveillance Ongoing scrutiny of a population (general population, study population, target population, etc.), generally using methods distinguished by their practicability, uniformity, and frequently their rapidity, rather than by complete accuracy. Surveillance, Population
D005260 Female Females
D005773 Gastroscopy Endoscopic examination, therapy or surgery of the interior of the stomach. Gastroscopic Surgical Procedures,Surgical Procedures, Gastroscopic,Gastroscopic Surgery,Surgery, Gastroscopic,Gastroscopic Surgeries,Gastroscopic Surgical Procedure,Gastroscopies,Procedure, Gastroscopic Surgical,Procedures, Gastroscopic Surgical,Surgeries, Gastroscopic,Surgical Procedure, Gastroscopic
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000359 Aftercare The care and treatment of a convalescent patient, especially that of a patient after surgery. After Care,After-Treatment,Follow-Up Care,Postabortal Programs,Postabortion,After Treatment,After-Treatments,Care, Follow-Up,Cares, Follow-Up,Follow Up Care,Follow-Up Cares,Postabortal Program,Program, Postabortal,Programs, Postabortal
D001706 Biopsy Removal and pathologic examination of specimens from the living body. Biopsies
D012189 Retrospective Studies Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons. Retrospective Study,Studies, Retrospective,Study, Retrospective
D012307 Risk Factors An aspect of personal behavior or lifestyle, environmental exposure, inborn or inherited characteristic, which, based on epidemiological evidence, is known to be associated with a health-related condition considered important to prevent. Health Correlates,Risk Factor Scores,Risk Scores,Social Risk Factors,Population at Risk,Populations at Risk,Correlates, Health,Factor, Risk,Factor, Social Risk,Factors, Social Risk,Risk Factor,Risk Factor Score,Risk Factor, Social,Risk Factors, Social,Risk Score,Score, Risk,Score, Risk Factor,Social Risk Factor

Related Publications

Young Bae Lee, and Jaeho Han, and Jeong Hyeon Cho, and Hong Sub Lee
May 2014, Southern medical journal,
Young Bae Lee, and Jaeho Han, and Jeong Hyeon Cho, and Hong Sub Lee
January 2013, PloS one,
Young Bae Lee, and Jaeho Han, and Jeong Hyeon Cho, and Hong Sub Lee
November 2014, Clinical endoscopy,
Young Bae Lee, and Jaeho Han, and Jeong Hyeon Cho, and Hong Sub Lee
March 2020, Gut and liver,
Young Bae Lee, and Jaeho Han, and Jeong Hyeon Cho, and Hong Sub Lee
July 2021, Gastrointestinal endoscopy clinics of North America,
Young Bae Lee, and Jaeho Han, and Jeong Hyeon Cho, and Hong Sub Lee
July 2019, Gastroenterology,
Young Bae Lee, and Jaeho Han, and Jeong Hyeon Cho, and Hong Sub Lee
April 1986, Gastrointestinal endoscopy,
Young Bae Lee, and Jaeho Han, and Jeong Hyeon Cho, and Hong Sub Lee
May 2014, World journal of gastrointestinal pathophysiology,
Young Bae Lee, and Jaeho Han, and Jeong Hyeon Cho, and Hong Sub Lee
July 2010, Gastrointestinal endoscopy,
Young Bae Lee, and Jaeho Han, and Jeong Hyeon Cho, and Hong Sub Lee
September 2021, Journal of gastric cancer,
Copied contents to your clipboard!