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Long-term extrapolative prognosis is presented, which is based on 30-year data on tick-borne encephalitis infection rates in the Krasnoyarsk Territory. Mathematical analysis of many-year ranges was performed later by a maximum entropy method with further frequency filtration, its results allowing to predict the infection rate. Disease rate changes for the last 4 years demonstrated that extrapolative prognosis based both on expert and mathematical assessment (by the entropy maximum method) agreed well with the real data.
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