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Experiments on white non-pure male mice have established that NA oxybutirate in doses 100 mg/kg and mexamine in doses 2.5 mg/kg possess antihypoxic properties in conditions of severe hypoxia corresponding to a height of 10 000 m. In a combined introduction of Na oxybutirate and mexamine in the above-mentioned doses there is an increase of their antihypoxic action. It was demonstrated that Na oxybutirate, mexamine and their combination exposes a distinct protective effect on the cortical neurons on rats in conditions of hypoxia. It is assumed that the protective action of the studied antihypoxants on the cortical neurons is realized with the aid of the same mechanisms as in a physiological adaptation to hypoxia.
V A Khokhlova, and
N P Bykov, and
P B Kazakova, and
R B Strelkov
April 1970,
Biulleten' eksperimental'noi biologii i meditsiny,
V A Khokhlova, and
N P Bykov, and
P B Kazakova, and
R B Strelkov
January 1967,
Doklady Akademii nauk SSSR,
V A Khokhlova, and
N P Bykov, and
P B Kazakova, and
R B Strelkov
August 2015,
Neural regeneration research,
V A Khokhlova, and
N P Bykov, and
P B Kazakova, and
R B Strelkov
January 1980,
Agressologie: revue internationale de physio-biologie et de pharmacologie appliquees aux effets de l'agression,
V A Khokhlova, and
N P Bykov, and
P B Kazakova, and
R B Strelkov
June 1978,
Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova,
V A Khokhlova, and
N P Bykov, and
P B Kazakova, and
R B Strelkov
January 1973,
Radiobiologiia,
V A Khokhlova, and
N P Bykov, and
P B Kazakova, and
R B Strelkov
January 1969,
Biulleten' eksperimental'noi biologii i meditsiny,
V A Khokhlova, and
N P Bykov, and
P B Kazakova, and
R B Strelkov
January 1979,
Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952),
V A Khokhlova, and
N P Bykov, and
P B Kazakova, and
R B Strelkov
November 1979,
Biulleten' eksperimental'noi biologii i meditsiny,
V A Khokhlova, and
N P Bykov, and
P B Kazakova, and
R B Strelkov
July 1991,
Neurochemical research,
